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Comparison of adsorption capacity and adsorption efficiency of diosmectite and charcoal on selected compounds that often cause acute intoxication in adult population of the Czech Republic
Mináriková, Michaela ; Martínková, Markéta (advisor) ; Mrízová, Iveta (referee)
In the treatment of acute intoxications, one of the treatment procedures is an antidote submission, e.g. diosmectite and activated charcoal, where an antidote is a substance which acts antagonistically and disturbingly with the toxic effect of a toxic substance. The aim of this work was to compare the adsorption capabilities of activated charcoal and diosmectite in selected model compounds which are the most common originators of acute intoxications in the adult population of the Czech Republic. The actual comparison of adsorption capabilities of these sorbents was preceded by issues search processing of ten groups of substances that cause the most acute intoxications and subsequent testing of the proposed method for future detailed testing of adsorption and adsorption efficiency of different sorbents. Of the ten groups of substances five model compounds were selected: dosulepin, acetylsalicylic acid, ibuprofen, promethazine and phenobarbital, on which adsorption of diosmectite, activated charcoal, and mixture of these sorbents was compared in the experimental part of this work. This comparison of the adsorption capabilities of sorbents was carried out not only under neutral conditions, but also in an alkaline and acidic environment which simulated physiological conditions in different parts of the...
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Killer plants in Prague and its surroundings: A guide to their diversity and hidden dangers
Kováříková, Kateřina ; Slovák, Marek (advisor) ; Novotný, Petr (referee)
The immobility of plants and their inability to escape from danger is compensated by the creation of various defence strategies, which are used mainly by toxic plants. The main goal of the bachelor's thesis is a literature review on the topic of poisonous (toxic) plants, both in the context of defence mechanisms and their importance for human society. The thesis deals with the description of the main groups of toxic plant compounds, summarizes their chemical composition, properties, distribution, and effects on the human body. The second half of the work is focused on the diversity of wild-growing but also of some cultivated toxic plants of our landscape with a specific focus on the flora of Prague and its immediate surroundings. It analyzes plant representatives from two families, important for the production of toxic secondary metabolites, in more detail. Specifically, they are the aubergine (Solanaceae) and buttercup (Ranunculaceae) families. Along with the description of partial representatives, their distribution, ecology, my work also describes the documented poisonings and use of poisonous plants in folk and modern medicine. The impetus for the creation of this work is the low awareness not only of the child population but also of adults, about the dangers, risks, and impact of these toxic...
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Comparison of adsorption capacity and adsorption efficiency of diosmectite and charcoal on selected compounds that often cause acute intoxication in adult population of the Czech Republic
Mináriková, Michaela ; Martínková, Markéta (advisor) ; Mrízová, Iveta (referee)
In the treatment of acute intoxications, one of the treatment procedures is an antidote submission, e.g. diosmectite and activated charcoal, where an antidote is a substance which acts antagonistically and disturbingly with the toxic effect of a toxic substance. The aim of this work was to compare the adsorption capabilities of activated charcoal and diosmectite in selected model compounds which are the most common originators of acute intoxications in the adult population of the Czech Republic. The actual comparison of adsorption capabilities of these sorbents was preceded by issues search processing of ten groups of substances that cause the most acute intoxications and subsequent testing of the proposed method for future detailed testing of adsorption and adsorption efficiency of different sorbents. Of the ten groups of substances five model compounds were selected: dosulepin, acetylsalicylic acid, ibuprofen, promethazine and phenobarbital, on which adsorption of diosmectite, activated charcoal, and mixture of these sorbents was compared in the experimental part of this work. This comparison of the adsorption capabilities of sorbents was carried out not only under neutral conditions, but also in an alkaline and acidic environment which simulated physiological conditions in different parts of the...
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