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Fotochemická degradace hypolipidemika atorvastatinu s využitím heterogenní fotokatalýzy.
VONEŠOVÁ, Adéla
The Bachelor s thesis is focused on hypolipidemic drugs statins and their representative atorvastatin. In the theoretical part of the thesis, the function of statins is introduced, studies about statins toxicity for freshwater organisms are presented, fundamentals of heterogeneous photocatalysis are explained and examples of usage of the method for pollutants degradation are given. Experimental part presents kinetics of atorvastatin degradation on TiO2 photocatalyst and a test of toxicity of atorvastatin photoproducts on a water plant (Lemna minor).
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Statiny - jejich použití, mechanismus účinku, vedlejší efekty. Atorvastatin a možnosti jeho fotochemické degradace v přírodních vodách.
PETRÁŇOVÁ, Pavla
The Bachelor´s thesis deals with a group of hypolipidemic drugs, statins. In the theoretical part, their development, characteristics, mechanism of action and side effects are presented. The experimental part is focused on one representant of statins, atorvastatin, its possible photochemical degradation in aqueous solution under light conditions relevant to natural waters, and a potential toxic effect of atorvastatin itself and of the mixture of products of atorvastatin photochemical degradation on a water plant Lemna minor.
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Photochemical Degradation of a Phenyl-urea Pesticide Chlorotoluron
ZEMANOVÁ, Martina
Chlorotoluron photochemical degradation in homogeneous phase (aqueous solutions) was studied. Photolysis by UV radiation, influence of metal (ferric, ferrous) ions, pH, and solvent composition on the reaction rate was investigated. Photosensitizing effect of humic samples was tested. Kinetic characteristics (rate constants, overall quantum yield), products of reactions and extent of mineralization was evaluated.
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