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Vliv supranutričních dávek organické formy selenu na vybrané krevní parametry králíků
MIRANDOVÁ, Marie
Selenium is an important essential mikroelement, that acts through a number of selenoproteins. Both it´s lack, and it´s plenty has a negative influence on the organism. Recently is used Se during the various diseases treatment of people with supranutritive dosages of this element. The presented thesis deals with the supranutritive dosages influence of Selenium concentration organic form (Chlorella, enlarged alga with selenium) in blood serum and selected rabbits blood parameters (hemoglobin and hematocrit level, leukocytes and erythrocytes, urea concentration, triglycerides, gamma value glutamyltransfers and total concentration of plasmatical proteins). Nine week experiment was performed on 18 rabbits, which were divided in to three experimental groups. Group 1 (control group) has received the selenium at a dosage of 0.15 mg / kg dry matter of feed, group 2 at a dosage of 0.3 mg / kg dry matter feed and group 3 at a dosage of 4.3 mg / kg of dry matter feed. During the experiment weren´t registered any clinical symptoms associated with the possible Se toxicity. Supranutritive dosages in the group 3 led to faster and statistically significant increase of the selenium concentration in the blood serum. Parameters of the hemopoiesis, the growth and the substantial metabolism had no influnece with supranutritive dosages in the groups 2 and 3. The results has not confirmed the clear positive or negative effect of selenium supranutritive dosages on selected blood parameters. The results show, that after rabbits supplementation are suitable recommended dosages of 0.15 mg Se / kg dry matter feed.
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