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Metodické přístupy v genové terapii na zvířecích modelech
 Šubrtová, Hana
This bachelor thesis deals with gene therapy as a possible treatment for many diseases. It summarizes general information on gene therapy how it is divided and a few important milestones in history that have significantly contributed to its development. Subsequently, this thesis focuses on the most commonly used vectors. There are listed and described their main advantages and disadvantages as well as examples of specific diseases for which the given gene carriers can be used as a treatment. This thesis also deals with methods most commonly used to detect gene mutation and summarizes model organisms suitable for gene therapy research. Finally, problematic areas associated with the application of gene therapy are described here.
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