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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Searching for Toll-like receptors agonists that would interact synergistically with ligands of phagocytic receptors and that could be used in cancer immunotherapy in human medicine
 LENZOVÁ, Zuzana
The goal of this thesis was to find agonists of Toll-like recptors that would interact with ligands of phagocytic receptors synergistically, would cause a strong suppresion of tumour growth, and could be safely used in human medicine.
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Study of clinically applicable cancer immunotherapy and their mechanisms
 GLASEROVÁ, Simona
The aim of this thesis was study of replacement of LPS in innate immunity based cancer immunotherapy. Application of poly (I:C) with mixture of mannan-SMCC + R-848.HCl leads to synergy, higher reduction of tumor growth and significant prolongation of survival. The significance and mechanism of action of neutrophils have also been studied within this therapy.
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