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Charakteristika přeměny larvální tukové tkáně v průběhu metamorfózy u \kur{Drosophila melanogaster}
 DANIELOVÁ, Adéla
The main aim of this master thesis is a characterization of morphological and physiological changes of larval adipose tissue in Drosophila melanogaster by using histological technics. Moreover, the expression of genes involved in lipolysis, mobilization of lipids, and ceramides metabolism were analyzed. The theoretical part of this thesis provides the current knowledge about the function of the larval fat body, the formation of lipofuscin, and the role of genes involved in lipid and ceramide metabolism. In the practical part, the results of characterization of adipocytes size changes and changes of size and quantity of lipofuscin granules and lipid droplets during the metamorphosis and post-metamorphosis, are introduced. Furthermore, it involves the analysis of genes expression being essential for lipid metabolism and mobilization of lipid storage.
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