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Histological investigation of placenta
VESELÁ, Jana
Histological examination of the placenta The thesis on the topic "Histological examination of the placenta" is divided into two parts - theoretical and practical.The theoretical part deals with description, development and function of the placenta. Emphasis is put on laboratory processing and examination of the placenta. Placental pathology, including inflammation of the placenta, defects in maturation and circulatory disorders of the placenta are described. The comparison of fetal disorders caused by selected malfunctions of the placenta, i.e. placental inflammation (due to infection by bacteria and viruses) and developmental disorders of the placenta with fetal hypoxia. Mothers suffering form diabetes mellitus may develop diabetic placentopathy consequently endangering the fetus.In the practical part three objectives are mentioned. The first objective is to master the methodology of laboratory processing of the placenta. This objective was accomplished, because I prepared 25 histological sections all by myself and I partially prepared 65 sections. The second objective is to define possible errors during laboratory processing of the placenta. I achieved this objective by recording all the possible errors I could witness. The third objective is to present some pathological findings in the placenta. This objective was met by taking photographs of the findings and describing them in the theoretical part. The presumed hypothesis that it is possible to diagnose inflammation of the placenta, hypoxic changes, degenerative changes and manifestations of placental malfunction on the basis of laboratory processing was confirmed.I applied the methodology of laboratory processing of the placenta which is being used in laboratories of the pathological department in the České Budějovice hospital.The results can be used both in practice and in teaching.

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