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Hormonally active substances in the aquatic environment and risk to aquatic organisms and human.
Duisembay, Zhuldyz ; Bušová, Milena (advisor) ; Ezechiáš, Martin (referee)
This bachelor thesis aims to investigate the presence, sources and impacts of hormonally active substances, or endocrine disruptors (EDs), in the aquatic environment. These substances, including long-lived persistent organic pollutants (POPs), e. g. pesticides and polycyclic aromatic hydrocarbons (PAHs), and non-persistent pollutants such as bisphenol A and alkyphenols, directly or indirectly affect the hormonal systems of aquatic organisms and humans. For instance, it was observed, that elevated concentrations of certain progestogens impact fertility, reproductive processes, induce transcriptional changes, and alter sex ratios within fish populations. Numerous studies in the field focus on evaluating the manifestation of EDs in water, their effects on behavior and vital functions of aquatic organisms and humans, and the challenges associated with their detection and removal from the wastewater discharged into the environment. Recent researches have revealed elevated concentrations of specific EDs in various regions, including Czech Republic (significant concentrations of levonorgestrel, megestrol acetate (MGA), drospirenone and dienogest were detected in Blanice river). This indicates a lack of regulations and potential difficulties in effectively removing these substances from water with...
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