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National Repository of Grey Literature

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Effect of 7-oxo-dehydroepiandrosterone on oxygen consumption of human PBMC ŠTEFKOVÁ, Kristýna Effect of 7-oxo-dehydroepiandrosterone (7-oxo-DHEA) on resting and noradrenaline stimulated oxygen consumption of human peripheral blood mononuclear cells (PBMC), isolated by gradient centrifugation, was studied using Clark oxygen electrode. It was found that, the 7-oxo-DHEA in concentration 10 umol/l has a thermogenic effect and increase resting metabolic rate of PBMC by more than 80 %. Oxygen consumption stimulated by noradrenaline was potentiated by 7-oxo-DHEA in concentration 0,1 umol/l by 39 %. Detailed record

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