National Repository of Grey Literature 4 records found  Search took 0.00 seconds. 
Terahertz Time-Domain Spectroscopy and Visualization of Biological Objects
Nedvědová, Marie ; Kužel,, Petr (referee) ; Vrba, Jan (referee) ; Provazník, Ivo (advisor)
This thesis deals with the methods of Terahertz (THz) spectroscopy to observe the kinetics of haemostatic materials used for supporting the native mechanism of haemostasis. The theoretical part follows the physical principles of THz time-domain spectroscopy (THz TDS), mentions the advantages and limitations of this method and its application possibilities for the characterization of biomedical materials. Further, there are specified properties of actual haemostats, described principles of their function and usage in practice, including their interaction with the living tissue. There were performed experiments monitoring the kinetics of physiologic reaction of the tissue adhesive based on the cyanoacrylates and absorbable haemostats. The mechanisms of monitored reactions were explained based on the physical-chemical principles that are used also for the kinetic models’ derivation. Modelling of the measured data results in the estimation of the parameters characterizing the observed samples. The most interesting parameter is the time constant of the reaction because of the possibility to compare reaction rates of different types of haemostats. The detailed analysis of this parameter is performed using the means of statistical methods. Tissue adhesive samples were measured by other spectroscopic and microscopic methods to compare the findings with the experimental results of the THz TDS. Data were processed using algorithms designed especially for this experiment and analysed using mathematical methods.
Methods of the emergency bleeding control and their use in rescue services
The theoretical part of this thesis refers to bleeding and the methods that are used to stop it. Descriptions of bleeding, physiological hemostasis, organism changes during hemorrhagic shock, methods of hemostasis, other treatment after temporary hemostasis and complications have all been included. This thesis contains well-known hemostasis methods such as the pressure bandage, but also new tools, for example the hemostatic gauze celox or newly developed tools like the Wound Stasis System. I set two goals for this research. The main goal was to find out which ways of hemostasis are used by ambulance services. The secondary goal was to compare the hemostasis equipment of the previously mentioned services. The research was done in a qualitative style. I used the managed talk method, which I addressed to 13 members of ambulance services. Each respondent belonged to a different organization from South Bohemia and South Moravia, they were all randomly chosen. Each of them answered the same 6 questions. They were asked about their training, equipment and hemostasis experiences. Furthermore, I was interested in their experience with the C-A-T equipment. The 13 subjects attending the survey are able to use all basic methods of hemostasis thanks to their training and equipment. Specifically referring to pressure on the injury, pressing pressure point, pressure bandages and tourniquets. Thanks to the equipment comparison I found out that ambulance services use the same equipment and the only differences concern the C-A-T system, the fixing pelvis belt and hemostasis gauze.

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