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Hereditary immunological diseases in dogs
KREJČOVÁ, Lenka
This thesis summarizes the most important findings of primary immunodeficiencies in different breeds of dogs, their genetic background, symptoms, their treatment options: canine leukocyte adhesion deficiency, trapped neutrophil syndrome, Pelger-Huet anomaly, severe combined immunodeficiency, grey collies syndrome, selective IgA deficiency, complement C3 deficiency and growth hormone deficiency with hypoplastic thymus in dogs. This diseases, often with autosomal recessive inheritance, are for affected individuals usually fatal. Research of primary immunodeficiencies in dogs is substantial also because it often serves as a model for similar studies human deficiencies.
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