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Biologická charakteristika dendritických buněk
 Coufalová, Karmela
This thesis deals about characteristics of dendritic cells. Dendritic cells are antigen presenting cells that can stimulate naive T and B cells and they can regulate immune response of organism. They differ from other cells in that they can express MHC I and MHC II molecules and in that they do not have surface immunoglobulines or lymphocytic and monocytic characters. Dendritic cells are spread nearly through all tissues of the organism. There are two main pathways myeloid and lymphoid. Dendritic cells have two forms: immature (tolerogenic) and matture (immunoregulatory). Follicular dendritic cells are special case of dendritic cells. They are morphologically similar to dendritic cells, but they have not the same origin. Dendritic cells can represent vector for immunotherapy of allergic diseases, infections, autoimmune diseases, tumor immunotherapy and they can play role also in transplantology. Recently, research deals with antitumor vaccination.
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