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Synthesis and Cytotoxicity of Fluorinated Amino Saccharides.
Hamala, Vojtěch
This work presents the synthesis of acetyl, propionyl, and butyrylesters of monofluorinated, difluorinated, and trifluorinated analogues\nof N-acetyl-d-glucosamine and N-acetyl-d-galactosamine, and theircytotoxicity expressed as IC50 values against the MDA-MB-231 cancer\ncell line (triple-negative breast cancer) along with their IC50 valuesagainst the HEK-293 non-cancerous cell line.
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