Home > Search Results: keywords:"extrakts"
Search:
Search Tips :: Advanced Search
Search collections:
Sort by: Display results: Output format:
National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Sledování imunomodulačních účinků extraktů z helminta na makrofágové buněčné kultuře
 ŘEŽÁBKOVÁ, Lucie
The main aim of the present study was to determine the immunomodulatory effects of extracts obtained from the commensal helminth, Hymenolepis diminuta, on in vitro rat macrophages. Here, I tested two types of crude extracts derived from various tapeworm's life stages (larval stages, adults) and excretory/secretory products (ES-products). The in vitro inflammatory model was induced by bacterial lipopolysaccharides (LPS) to compare the results with normal state of macrophages. To monitoring immune response, I analysed the relative gene expressions of several cytokines TNF, IL-10, IL-1; signal transducer and activator of transcription STAT6 as well as IL-17re using by qPCR. The presence of adult extracts caused no obvious immune response of macrophages. The larval extract and ES-products induced an inflammatory response. All three types of compounds derived from H. diminuta reduced the inflammation of macrophages influenced by LPS.
Detailed record

Interested in being notified about new results for this query?
Subscribe to the RSS feed.
Digital Repository :: Search :: Submit :: Personalize :: Help
Powered by Invenio v1.1.2
Maintained by admin.invenio@techlib.cz
This site is also available in the following languages:
Česky  English