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Neuropsychological profile in idiopatic generalized epilepsy (IGE)
Živnůstka, Miroslav ; Javůrková, Alena (advisor) ; Rolederová, Iva (referee)
Title: Neuropsychological profile in patients with idiopathic generalized epilepsy Author: Miroslav Živnůska Thesis supervisor: PhDr. Alena Javůrková, Ph.D. Consultant: PhDr. Jaroslava Raudenská, Ph.D. Pages: 60 Number of resources: 56 Idiopathic generalized epilepsy (IGE) is an epilepsy of genetic or unknown origin. It is divided into four syndromes: childhood absences (CAE), juvenile absences (JAE), juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic-clonic seizures (GTCS). Some studies have suggested that patients with IGE may exhibit deficits in cognitive domains such as intelligence, attention, memory, executive function, motor function, and speech function. The most affected area appeared to be the domain of execution, specifically the ability of verbal fluency. Medications, depression, impaired quality of life and other risk factors can also contribute significantly to cognitive impairment. Moreover, the siblings of these patients may also show a slight decrease in performance in neuropsychological tests. In addition, significant brain changes were found in patients with IGE, especially in the thalamus. This work sought to map the neuropsychological profile and affectivity in patients with IGE and their siblings, that was compared with a healthy control group. Furthermore,...
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Neuropsychological profile in idiopatic generalized epilepsy (IGE)
Živnůstka, Miroslav ; Javůrková, Alena (advisor) ; Rolederová, Iva (referee)
Title: Neuropsychological profile in patients with idiopathic generalized epilepsy Author: Miroslav Živnůska Thesis supervisor: PhDr. Alena Javůrková, Ph.D. Consultant: PhDr. Jaroslava Raudenská, Ph.D. Pages: 60 Number of resources: 56 Idiopathic generalized epilepsy (IGE) is an epilepsy of genetic or unknown origin. It is divided into four syndromes: childhood absences (CAE), juvenile absences (JAE), juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic-clonic seizures (GTCS). Some studies have suggested that patients with IGE may exhibit deficits in cognitive domains such as intelligence, attention, memory, executive function, motor function, and speech function. The most affected area appeared to be the domain of execution, specifically the ability of verbal fluency. Medications, depression, impaired quality of life and other risk factors can also contribute significantly to cognitive impairment. Moreover, the siblings of these patients may also show a slight decrease in performance in neuropsychological tests. In addition, significant brain changes were found in patients with IGE, especially in the thalamus. This work sought to map the neuropsychological profile and affectivity in patients with IGE and their siblings, that was compared with a healthy control group. Furthermore,...
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