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Design of cylindrical apparatus for determination of directions of reinforcing fibres in aorta in its deformed state
Král, Martin ; Vaverka, Jiří (referee) ; Burša, Jiří (advisor)
This bachelor thesis deals with the design of cylindrical apparatus, which allows the cont- rolled biaxial deformation of a cylindrical sample of the aorta. This apparatus is designed to determine the direction of collagen fibers in the deformed aorta. The theoretical part of the thesis is focused mainly on description of the structure and mechanical properties of the wall of the aorta. In the design part, attention is paid to the design of the cylindrical apparatus. In the conclusion, the deformation of the cylindrical sample of the abdominal aorta from the pig is carried out on the apparatus and its strain is measured.
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Design of apparatus for determination of directions of reinforcing fibres in soft biological tissues in their deformed state
Sodomka, Tomáš ; Vaverka, Jiří (referee) ; Burša, Jiří (advisor)
The Bachelor´s thesis is focused on the determination of directions of collagen fibres in elastic arteries. The first aim of this thesis is a general introduction into soft tissue mechanics with turning attention to connective tissue where collagen fibres are their inseparable part. Also the thesis introduces arrangement of collagen fibres, their waviness and how the waviness thwarts determination of direction of fibres. The second aim is a design and test of the mechanical apparatus, which is able to stretch a squared aortic sample in two perpendicular directions (independently on each other) up to the relative deformation of 30 %. Design of the apparatus allows the sample to be dipped into the formaldehyde solution, which fixes the deformation. Consequent histologic sections of the sample will be used for the determination of global directions of collagen fibres in the aorta. The apparatus is designed to simulate conditions in a human or animal body where aorta is axially pre-stretched and at the same time expanded in the radial direction by blood pressure.
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Design of cylindrical apparatus for determination of directions of reinforcing fibres in aorta in its deformed state
Král, Martin ; Vaverka, Jiří (referee) ; Burša, Jiří (advisor)
This bachelor thesis deals with the design of cylindrical apparatus, which allows the cont- rolled biaxial deformation of a cylindrical sample of the aorta. This apparatus is designed to determine the direction of collagen fibers in the deformed aorta. The theoretical part of the thesis is focused mainly on description of the structure and mechanical properties of the wall of the aorta. In the design part, attention is paid to the design of the cylindrical apparatus. In the conclusion, the deformation of the cylindrical sample of the abdominal aorta from the pig is carried out on the apparatus and its strain is measured.
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Design of apparatus for determination of directions of reinforcing fibres in soft biological tissues in their deformed state
Sodomka, Tomáš ; Vaverka, Jiří (referee) ; Burša, Jiří (advisor)
The Bachelor´s thesis is focused on the determination of directions of collagen fibres in elastic arteries. The first aim of this thesis is a general introduction into soft tissue mechanics with turning attention to connective tissue where collagen fibres are their inseparable part. Also the thesis introduces arrangement of collagen fibres, their waviness and how the waviness thwarts determination of direction of fibres. The second aim is a design and test of the mechanical apparatus, which is able to stretch a squared aortic sample in two perpendicular directions (independently on each other) up to the relative deformation of 30 %. Design of the apparatus allows the sample to be dipped into the formaldehyde solution, which fixes the deformation. Consequent histologic sections of the sample will be used for the determination of global directions of collagen fibres in the aorta. The apparatus is designed to simulate conditions in a human or animal body where aorta is axially pre-stretched and at the same time expanded in the radial direction by blood pressure.
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