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Comparison of sensitivity of Bacillus subtilis and Clostridium difficile against selected chemical ingredients.
Šlitrová, Barbora ; Ing.Veronika Holá, Ph.D. (referee) ; Omelková, Jiřina (advisor)
Sporicidal activity of disinfectants is tested on Bacillus subtilis spores according to ČSN EN 13704 standard. Until December 2007, 10 countries encountered outbreaks and 7 additional countries had endemic cases of Clostridium difficile-associated disease due to hypervirulent strain C. difficile PCR ribotype 027. This outbreak of CDAD with increased severity and mortality is spread as typical nosocomial infection. Clostridium difficile spores can persist on dry surfaces for 5 months. Therefore it is important to compare the effectiveness of disinfectants on both strains and find out whether Bacillus subtilis is the only proper microorganism for testing the sporicidal activity.
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Comparison of the biocidal activity of disinfectants against biofilm
Šlitrová, Barbora ; Votava,, Miroslav (referee) ; Omelková, Jiřina (advisor)
A common vector of nosocomial infections is Pseudomonas aeruginosa. This opportunistic pathogen is resistant against different classes of antibiotics as well as against biocides. Some P. aeruginosa strains are able to form biofilm. The biofilm formation on medical devices represent a common occurrence that can lead to serious illness and death. Bacteria in biofilms are more resistant than their planktonic counterparts. Therefore it is important to find disinfectants that will be effective also against biofilm. Bactericidal efficacy of four disinfectants has been evaluated on biofilm and on planktonic forms of P. aeruginosa.
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Comparison of the biocidal activity of disinfectants against biofilm
Šlitrová, Barbora ; Votava,, Miroslav (referee) ; Omelková, Jiřina (advisor)
A common vector of nosocomial infections is Pseudomonas aeruginosa. This opportunistic pathogen is resistant against different classes of antibiotics as well as against biocides. Some P. aeruginosa strains are able to form biofilm. The biofilm formation on medical devices represent a common occurrence that can lead to serious illness and death. Bacteria in biofilms are more resistant than their planktonic counterparts. Therefore it is important to find disinfectants that will be effective also against biofilm. Bactericidal efficacy of four disinfectants has been evaluated on biofilm and on planktonic forms of P. aeruginosa.
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Comparison of sensitivity of Bacillus subtilis and Clostridium difficile against selected chemical ingredients.
Šlitrová, Barbora ; Ing.Veronika Holá, Ph.D. (referee) ; Omelková, Jiřina (advisor)
Sporicidal activity of disinfectants is tested on Bacillus subtilis spores according to ČSN EN 13704 standard. Until December 2007, 10 countries encountered outbreaks and 7 additional countries had endemic cases of Clostridium difficile-associated disease due to hypervirulent strain C. difficile PCR ribotype 027. This outbreak of CDAD with increased severity and mortality is spread as typical nosocomial infection. Clostridium difficile spores can persist on dry surfaces for 5 months. Therefore it is important to compare the effectiveness of disinfectants on both strains and find out whether Bacillus subtilis is the only proper microorganism for testing the sporicidal activity.
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