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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Trends in the Consumption of a chosen ATC Group A10AA (inhibitors HMG-CoA reductase) in the period 2005-2015 in the Czech Republic
 Freimann, Antonín ; Lešetický, Ondřej (advisor) ; Železo, Eduard (referee)
The thesis deals with trends of drug consumption for the ATC group C10A (HMG-CoA reductase) in the Czech Republic in the years 2005 - 2015. The goal of this work is to analyse the consumption of statins (cholesterol lowering drugs), as well as to analyse the consumption trends (expressed in terms of prescribed daily doses) and subsequently explain the causes of the detected trends. The main method used in this work is the analysis and interpretation of data provided by the State Institute for Drug Control (SUKL). Individual consumption data sets are compared to each other and global trends are inferred based on the obtained results. In the practical part I analyse the consumption for the individual ATC groups according to their increasing lipid-lowering efficacy, according to the pharmaceutical companies involved and according to the experts' recommendations (within the framework of cardiovascular disease treatment). The conclusion of my work shows that the overall drug consumption for the the studied ATC group (given by the DDD/package total) was steadily increasing during the studied period while the consumption expressed in financial units was decreasing (ie. the financial burden on the health system was reduced). The total number of sold packages shows a slight decrease due to the sale of bigger packages with more powerful statins during the studied period.
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Trends in the Consumption of Drugs Used for Treatment of Diabetes over the Period 2005-2010
 Štipčáková, Lucie ; Lešetický, Ondřej (advisor) ; Střítecký, Rudolf (referee)
This diploma thesis presents an overview of current trends in the consumption of drugs for diabetes treatment in the Czech Republic, summarizes the current drug therapy recommendations in the context of professional medical societies and points to future developments and trends. Diabetes in recent years is referred as an epidemic of 21 century. Constantly increasing prevalence alarms professional society to active approach to address this issue. Cost of diabetes treatment grow every year and make 20 billion CZK a year. 10 to 15% from this amount are pharmacotherapy expenses. This amount represents about 7% of total expenditure on health. Total expenses for diabetes drugs reached CZK 2.4 billion in 2010, which represents 58 % growth compared to 2005. An average diabetic consumes about 10 packs of drugs per year, which is about two more than in 2005. Unhealthy lifestyle, increasing incidence of child's obesity, active screening of high-risk people and longer life expectancy of diabetics predispose to a growing trend in the consumption of drugs.
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