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National Repository of Grey Literature

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Synthesis of conformationally locked carbocyclic nucleosides with norbornane as pseudosugar moiety Dejmek, Milan ; Hřebabecký, Hubert ; Šála, Michal ; Dračínský, Martin ; Nencka, Radim We describe the chemical synthesis of three novel structural types of conformationally locked carbocyclic nucleosides with norbornane as sugar surrogate. The presented structures bear hydroxymethyl, nucleobase or both in the bridgehead positions of the norbornane pseudosugar and thus adopt three different conformations of the cyclopentane ring – North, South, and East. Detailed record

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