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Optimalization of preparation of bifunctional organocatalysts derived from alkaloids
Formánek, Bedřich ; Veselý, Jan (advisor) ; Drahoňovský, Dušan (referee)
This bachelor thesis deals with the preparation of C−9 Cinchona alkaloid derivatives, which are used in wide variety of asymmetric transformations. First goal is comparison of synthetic aproaches and their effectiveness. In particular of C−9 amino derivatives. This part also examines possible optimization of synthesis individual steps. Second goal of bachelor thesis focuses on preparation bifunctional catalysts based on Cinchona alkaloids.

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