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National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Optimization of hydrogel carrier for assessment of antimicrobial activity of biocidal surfaces
 Antálek, Adam ; Jančovičová, Viera (referee) ; Králová, Marcela (advisor)
This diploma thesis deals with the optimization of the composition and properties of hydrogels as carriers of microbial populations for the evaluation of the antimicrobial effects. There are standardized procedures for assessing antimicrobial surfaces, but they have shortcomings, such as the necessity of testing exclusively under laboratory conditions. In the presented work, a new evaluation methodology is proposed, which utilizes a modified resazurin test and hydrogels as platforms for bacterial seeding, enabling the assessment of the investigated antimicrobial surface. The composition and properties of hydrogel carriers were successfully optimized with respect to their swelling and mechanical properties, thereby improving recovery compared to standardized procedures. Tests on antimicrobial materials showed that the bacteria used on hydrogels continued to grow, rendering the use of composite hydrogels for this application impractical.
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