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The analysis of aberrations in the localization of the radiated fields during irradiation of the patients with rectum tumors by EPID method
HARTMANOVÁ, Magda
The presented thesis deals with the analysis of deviations in radiation fields during the irradiation of the patients with rectal tumors. The first part of the thesis is focused on the current problems connected with rectal and rectosigmoid cancer both in the Czech Republic and worldwide. It also includes the description of risk factors, characterisation of the given type oftumor, manifestation of the disease as well as the prognosis. What is also tackled is the prevention, which is important and often neglected.It was necessary to mention the possibilities of screening and dispensarisation programs. The next part deals with the diagnostic process (from anamnesis to specialised examinations) as well as the therapy. Chemotherapy and surgery are mentioned only marginally whereas radiotherapy, including its planning and methods, is dealt with in a more detailed way. The main part consists of the analysis of deviations in radiation fields. The deviations have been obtained by means of EPID (electron portal image device) in a sample of patients with rectal and rectosigmoid cancer who are treated with the use of radiotherapy at the oncological ward of the Hospital České Budějovice, Inc. The maximum, minimum and average deviation in the localization of radiation fields were assessed statistically, by means of the khi-quadrate test. The results obtained will be submitted to the oncological ward of the Hospital České Budějovice, Inc., where they can contribute to the assessment of radiotherapy quality. The thesis includes supplements such as portal images and tables with graphs indicating the development of the incidence and mortality for the chosen diagnosis within the entire population.
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