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40/5000 Fine particles produced by the stove
Škvařil, Ondřej ; Baláš, Marek (referee) ; Pospíšil, Jiří (advisor)
This master thesis deals with problematics of fine particles produced during combustion in fireplace stoves. The theoretical part is focused on the analysis of the atmosphere, health consequences, solid pollutants, the formation of particles (origin), particle separation and how they are regulated by laws. Theoretical section of the thesis addresses analysis of biomass and its combustion. In the applied section are listed given methods of the particles measuring according to regulations, common errors during measurement and methods of identification of measured fine particles. Then follow specific measurements of the formed very fine particles produced by the SMPS method. Subsequently, the results of the measurement are evaluated and summarized in the conclusion.
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Vizualization of flow of fibers from insulation mineral wool
Kedajová, Kristýna ; Elcner, Jakub (referee) ; Lízal, František (advisor)
One of the most used insulation materials of our time is mineral wool. As with formerly used asbestos, not all the health impacts of mineral wool fibers inhalation are known. The aim of this thesis is to gather findings relating to the transport of aerosols, their deposition in human airways and to obtain and statistically evaluate experimental data from the visualization of fibres in the glass tube resembling human airways. This data can improve understanding of the relation between glass fibres action and possible health hazard.
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Numerical model of aerosol formation during biomass combustion
Chýlek, Radomír ; Lízal, František (referee) ; Masaryk, Michal (referee) ; Pospíšil, Jiří (advisor)
This thesis focuses on creating a numerical model to describe the thermal impact on biomass with aerosol formation. The model is based on the modification of the network-based CPD model and is intended for simulating the thermal decomposition of biomass. The objective of this work was to verify the functionality of the model and perform comprehensive validation through laboratory measurements. The validation involved analyzing lignocellulosic biomass and its individual structural materials. The validation results confirmed the model’s ability to simulate slow pyrolysis with good agreement with experimental data. Prior research focused on determining the composition of biomass and selecting an appropriate model for biomass combustion/pyrolysis simulation. The thesis also describes other tested approaches and improvements to the CPD model.
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Aerosol and microbial microclimate of clean rooms
Stojanová, Barbora ; Andrys, Petr (referee) ; Rubina, Aleš (advisor)
Master´s thesis deals with the issue of internal microclimate of clean rooms. The experimental part focuses on aerosol and microbial microclimate. Different operating and intervention rooms were measured and then evaluated whether the cleanroom would comply with the standard cleanliness class even in normal operation after previous validations. The microbial examination of different clean spaces investigated the extent to which the exact passive fall method and its evaluation were time-dependent. From the data the correct desing of the air-conditioning system and its subsequent realization and regultion were verified. The theoretical part describes requirements for clean rooms according to SÚKL-LEK 17 and ČSN EN ISO 14644-1. In addition, a detailed methodology of the procedure of air-conditioning implementation is elaborated to the final validation and testing of clean rooms.
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Inhalers and nebulizers for treatment of diseases caused by bacteria
Kánská, Jana ; Bělka, Miloslav (referee) ; Lízal, František (advisor)
One of today's problems that threaten the future of humanity is the ever-increasing bacterial resistance to antibiotics. It is therefore necessary to look for new treatments against bacterial diseases. A possible alternative to antibiotics is treatment with bacteriophages. This work aims to help to increase the effectiveness of bacteriophage treatment. The first part of the thesis contains a survey of inhalation devices and focuses in particular on the devices most suitable for phage therapy, i.e. treatment with bacteriophages. Furthermore, there is a brief overview of phage therapy and the studies already conducted on this topic. In the experimental section, three experiments are described. In the first two experiments, the model drugs were liposomes. First, their size distributions were measured after nebulization using two types of nebulizers (jet and mesh). Next, the deposition of liposomes after nebulization was monitored in a simplified lung model. In the third experiment, phage lysates were nebulized using three different nebulizers (two jet and one mesh). The nebulized lysates were captured in a sterile tube so that the stability of the phages after nebulization could be subsequently evaluated. The experimental part showed that during liposome nebulization, the jet nebulizer produced more FPF than the mesh nebulizer. It was further found that during nebulization with the jet nebulizer, almost the same amount of aerosol entered the lungs as remained in the mouthpiece, with a large amount also remaining in the nebulizer itself. A third experiment showed that neither nebulizer substantially degraded the phage lysate.
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Geoengineering as a solution to climate change
Pól, Daniel ; Elcner, Jakub (referee) ; Lízal, František (advisor)
The bachelor thesis contains short summary of current knowledge about the geoengineering methods. The research includes their history and all experiments made so far and describes the behaviour and potential utilization of aerosols in the atmosphere. Following chapters characterize four main methods of active geoengineering together with evaluation of their advantages and disadvantages. The last part of the thesis is devoted to the geopolitical impacts of geoengineering activities on society.
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Inhalers and nebulizers for treatment of diseases caused by bacteria
Kánská, Jana ; Bělka, Miloslav (referee) ; Lízal, František (advisor)
One of today's problems that threaten the future of humanity is the ever-increasing bacterial resistance to antibiotics. It is therefore necessary to look for new treatments against bacterial diseases. A possible alternative to antibiotics is treatment with bacteriophages. This work aims to help to increase the effectiveness of bacteriophage treatment. The first part of the thesis contains a survey of inhalation devices and focuses in particular on the devices most suitable for phage therapy, i.e. treatment with bacteriophages. Furthermore, there is a brief overview of phage therapy and the studies already conducted on this topic. In the experimental section, three experiments are described. In the first two experiments, the model drugs were liposomes. First, their size distributions were measured after nebulization using two types of nebulizers (jet and mesh). Next, the deposition of liposomes after nebulization was monitored in a simplified lung model. In the third experiment, phage lysates were nebulized using three different nebulizers (two jet and one mesh). The nebulized lysates were captured in a sterile tube so that the stability of the phages after nebulization could be subsequently evaluated. The experimental part showed that during liposome nebulization, the jet nebulizer produced more FPF than the mesh nebulizer. It was further found that during nebulization with the jet nebulizer, almost the same amount of aerosol entered the lungs as remained in the mouthpiece, with a large amount also remaining in the nebulizer itself. A third experiment showed that neither nebulizer substantially degraded the phage lysate.
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40/5000 Fine particles produced by the stove
Škvařil, Ondřej ; Baláš, Marek (referee) ; Pospíšil, Jiří (advisor)
This master thesis deals with problematics of fine particles produced during combustion in fireplace stoves. The theoretical part is focused on the analysis of the atmosphere, health consequences, solid pollutants, the formation of particles (origin), particle separation and how they are regulated by laws. Theoretical section of the thesis addresses analysis of biomass and its combustion. In the applied section are listed given methods of the particles measuring according to regulations, common errors during measurement and methods of identification of measured fine particles. Then follow specific measurements of the formed very fine particles produced by the SMPS method. Subsequently, the results of the measurement are evaluated and summarized in the conclusion.
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Vizualization of flow of fibers from insulation mineral wool
Kedajová, Kristýna ; Elcner, Jakub (referee) ; Lízal, František (advisor)
One of the most used insulation materials of our time is mineral wool. As with formerly used asbestos, not all the health impacts of mineral wool fibers inhalation are known. The aim of this thesis is to gather findings relating to the transport of aerosols, their deposition in human airways and to obtain and statistically evaluate experimental data from the visualization of fibres in the glass tube resembling human airways. This data can improve understanding of the relation between glass fibres action and possible health hazard.
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