National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Adenosine-induced cell death in imaginal disc cells of \kur{Drosophila melanogaster}
KOUBOVÁ, Justina
In the present study, we investigated the mechanism of adenosine-induced apoptosis in Drosophila imaginal disc cell line using the overexpression and silencing of several candidate genes. Our results indicate that the cell death is associated with the activity of c-Jun N-terminal kinase (JNK).
Genetic screening for the dominant suppressors of adgf-a mutant phenotype in Drosophila
HARTMANN, David
Extracellular adenosine is an important signaling molecule in various physiological processes. When not regulated properly it can cause various pathologies such as Severe Combined Immunodeficiency. To study the effects of increased extracellular adenosine level a Drosophila model has been established. This model is based on mutation in the main adenosine deaminase gene in Drosophila (ADGF-A, Adenosine Deaminase-related Growth Factor A). This work is a consequence of large screening for the suppressors of adgf-a mutant phenotype and presents a more detailed study of 3 previously identified regions containing dominant suppressors.

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