National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Vliv signalizace extracelulárního adenosinu na model Huntingtonovy choroby v \kur{Drosophila melanogaster}
FILIP, Tomáš
Adenosine is a ubiquitous metabolite with multiple physiological functions in organisms. In this thesis, I studied the effect of extracellular adenosine on Huntington´s disease (HD) model Drosophila melanogaster. I show that extracellular Adenosine signaling mitigates HD pathology by observing three main types of symptoms of the disease in Drosophila. The results suggest that the mechanism involves Drosophila melanogaster adenosine receptor signaling.

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