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Knee osteoarthritis: a biological response to medication class SYSADOA
Kurková, Eva ; Jelen, Karel (advisor) ; Tlapáková, Eva (referee)
Author: Bc. Eva Kurková Title: Knee osteoarthritis: a biological response to medication class SYSADOA Problem definition: Knee osteoarthritis is a degenerative joint disease which belongs to the most common musculoskeletal diseases. The disease is associated with pain of the knee joints, which causes patients' limitations in activities of daily living. Therefore, the objective of the treatment of osteoarthritis is to reduce the pain and a progression of the disease. To achieve these aims, conservative or surgical methods are used. The conservative methods include, among others, the pharmacological treatment. Since the medicaments from the class SYSADOA are easily available we can use them during treatment. Aim of the thesis: The aim of the thesis is to determine the effect of SYSADOA medication on the 2nd and 3rd degree of the knee osteoarthritis. The effect is determined by patients' subjective evaluations and by the changes of the rheological properties of the knee joint. Method: The survey contains an anamnesis questionnaire and the clinical examination of the knee joint. The rheological properties of the knee joint are evaluated by a special device - knee rheometer that non-invasively and painlessly measures the dependence of the passive resistance of the knee joint on its bending angle. To...
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The influence of pharmacological substances from the SYSADOA group on knee osteoarthritis.
Pavlová, Lenka ; Kubový, Petr (advisor) ; Jelen, Karel (referee)
Title: The influence of pharmacological substances from the SYSADOA group on knee osteoarthritis. Objectives: The aim of this work is to determine the effect of three - month usage of pharmacological substances from the SYSADOA group on the subjective perception of the difficulties associated with the knee osteoarthritis and on the reological changes in the joint. Methods: In collaboration with rehabilitation and orthopedic centres 18 probands with knee osteoarthritis in the second degree were obtained. These probands were divided into two groups - the experimetal group (including those who have taken Proenzi 3 plus) and the control group (including those who have taken placebo). With all the pacients the input clinical examination and the medical history were done. Probands had been using these preparations for twelve weeks. After this time, the changes in the subjective perception using the WOMAC test and reological changes in the joint were evaluated, using a special knee rheometer. Results: The results of objectively measured parameters clearly proved that the Proenzi 3 plus has a positive effect on the rheological properties of the knee osteoarthritis. The experimental group had a statistically significant improvement in both of these parameters, as opposed to the control group. Concerning...
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The influence of pharmacological substances from the SYSADOA group on knee osteoarthritis.
Pavlová, Lenka ; Kubový, Petr (advisor) ; Jelen, Karel (referee)
Title: The influence of pharmacological substances from the SYSADOA group on knee osteoarthritis. Objectives: The aim of this work is to determine the effect of three - month usage of pharmacological substances from the SYSADOA group on the subjective perception of the difficulties associated with the knee osteoarthritis and on the reological changes in the joint. Methods: In collaboration with rehabilitation and orthopedic centres 18 probands with knee osteoarthritis in the second degree were obtained. These probands were divided into two groups - the experimetal group (including those who have taken Proenzi 3 plus) and the control group (including those who have taken placebo). With all the pacients the input clinical examination and the medical history were done. Probands had been using these preparations for twelve weeks. After this time, the changes in the subjective perception using the WOMAC test and reological changes in the joint were evaluated, using a special knee rheometer. Results: The results of objectively measured parameters clearly proved that the Proenzi 3 plus has a positive effect on the rheological properties of the knee osteoarthritis. The experimental group had a statistically significant improvement in both of these parameters, as opposed to the control group. Concerning...
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Influence of drugs from the group SYSASOA for knee osteoarthrosis
Milerová, Klára ; Kubový, Petr (advisor) ; Lopot, František (referee)
Tittle:Influence of drugs from the group SYSADOA for knee osteoarthrosis Objectives:The aim of the thesis is to evaluate the effect of three months use of drugs from the group SASADOA on subjective perception of the difficulties associated with knee osteoarthritis and to determine the intensity of gonarthrosis progression in connection with knee cartilage width. Methods:For the study18 probands were obtained from rehabilitation and orthopedic institutions in Prague. The criterion for recruitmen t was knee joint osteoarthrosis of II. degree. For all participants there was conducted input kinesiology analysis and clinical examination, patient's medical history and filled in WOMAC questionnaire. All participants were sent for an X-ray of the knee. Group of probands was randomly divided into two groups. An experimental group was taking Proenzi 3 plus, a control group was taking placebo. Both groups were taking medications for 12 weeks. After this time the probands arrived to check- up and second filling in of the WOMAC questionnaire. The experimental group that had been taking Proenzi 3 plus received placebo for additional 12 weeks, the control group received Proenzi 3 Plus. After finishing preparations all probands were invited to the last visit where they underwent follow-up examination, the third...
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Knee osteoarthritis: a biological response to medication class SYSADOA
Kurková, Eva ; Jelen, Karel (advisor) ; Tlapáková, Eva (referee)
Author: Bc. Eva Kurková Title: Knee osteoarthritis: a biological response to medication class SYSADOA Problem definition: Knee osteoarthritis is a degenerative joint disease which belongs to the most common musculoskeletal diseases. The disease is associated with pain of the knee joints, which causes patients' limitations in activities of daily living. Therefore, the objective of the treatment of osteoarthritis is to reduce the pain and a progression of the disease. To achieve these aims, conservative or surgical methods are used. The conservative methods include, among others, the pharmacological treatment. Since the medicaments from the class SYSADOA are easily available we can use them during treatment. Aim of the thesis: The aim of the thesis is to determine the effect of SYSADOA medication on the 2nd and 3rd degree of the knee osteoarthritis. The effect is determined by patients' subjective evaluations and by the changes of the rheological properties of the knee joint. Method: The survey contains an anamnesis questionnaire and the clinical examination of the knee joint. The rheological properties of the knee joint are evaluated by a special device - knee rheometer that non-invasively and painlessly measures the dependence of the passive resistance of the knee joint on its bending angle. To...
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