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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Bioinformatics Tool for Prediction of Protein Solubility
 Čermák, Jiří ; Hon, Jiří (referee) ; Martínek, Tomáš (advisor)
To achieve cheaper and more efficient protein production, we must be able to predict protein solubility. In this thesis, we describe creation of bioinformatic data sets based on Target Track and eSol databases, we test the features used in existing protein solubility prediction tools and create a new predictor. Even though we fail to create an effective prediction tool we find out that in most cases the old features tested on the new data do not correlate with protein solubility as strongly as others repot in older and smaller datasets.
Detailed record
Bioinformatics Tool for Prediction of Protein Solubility
 Čermák, Jiří ; Hon, Jiří (referee) ; Martínek, Tomáš (advisor)
To achieve cheaper and more efficient protein production, we must be able to predict protein solubility. In this thesis, we describe creation of bioinformatic data sets based on Target Track and eSol databases, we test the features used in existing protein solubility prediction tools and create a new predictor. Even though we fail to create an effective prediction tool we find out that in most cases the old features tested on the new data do not correlate with protein solubility as strongly as others repot in older and smaller datasets.
Detailed record

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