National Repository of Grey Literature 6 records found  Search took 0.01 seconds. 
Analysis of electrical and thermal effects during electroporation
Novotná, Veronika ; Richter, Aleš (referee) ; Hána,, Karel (referee) ; Červinka, Dalibor (advisor)
This dissertation thesis describes a phenomenon called electroporation. It is about its theoretical aspects as well as about modeling of processes in the tissue during electroporation. Further, it describes the technical design of two developed unique experimental generators of DC and AC pulses for electroporation purposes. It also includes a description of experiments which were done using discussed generators.
Modeling of the thermal effects on living tissue during electroporation process
Kafka, Roman ; Cipín, Radoslav (referee) ; Červinka, Dalibor (advisor)
The work deals with the current state of knowledge of heat transfer in living tissue. It is described here what the distribution of heat is affected with and the existing calculation options. For solving Pennes equation using finite element method COMSOL Multiphysics 5.4 is used. From the current state of the published studies, three are selected and described, each using a different approach. Based on the benefit of each of the studies described, a simple model of its own that simulates an ablation catheter attached to cardiac tissue is solved. A change in electrical conductivity as a function of the electric field intensity is taken into account, but there is also a comparison with anisotropic tissue that has electrical conductivity in different directions. The result of the calculation is voltage distribution, density of electric current and losses, temperature distribution in the model at several time points and graph of temperature development over time.
Simulation of electroporation effect in the heart for various application catheter designs
Kafka, Roman ; Hemzal, Martin (referee) ; Novotná, Veronika (advisor)
This master thesis describes modeling of electric and thermal fields in tissue during cardiac ablation based on irreversible electroporation. It is about basic principles and laws that applies to this problematics. Further, it describes the electric and thermal difference between DC and AC electroporation pulses. The follow-up work presents many simulation models of new cardiac catheters developed with research team.
Simulation of electroporation effect in the heart for various application catheter designs
Kafka, Roman ; Hemzal, Martin (referee) ; Novotná, Veronika (advisor)
This master thesis describes modeling of electric and thermal fields in tissue during cardiac ablation based on irreversible electroporation. It is about basic principles and laws that applies to this problematics. Further, it describes the electric and thermal difference between DC and AC electroporation pulses. The follow-up work presents many simulation models of new cardiac catheters developed with research team.
Modeling of the thermal effects on living tissue during electroporation process
Kafka, Roman ; Cipín, Radoslav (referee) ; Červinka, Dalibor (advisor)
The work deals with the current state of knowledge of heat transfer in living tissue. It is described here what the distribution of heat is affected with and the existing calculation options. For solving Pennes equation using finite element method COMSOL Multiphysics 5.4 is used. From the current state of the published studies, three are selected and described, each using a different approach. Based on the benefit of each of the studies described, a simple model of its own that simulates an ablation catheter attached to cardiac tissue is solved. A change in electrical conductivity as a function of the electric field intensity is taken into account, but there is also a comparison with anisotropic tissue that has electrical conductivity in different directions. The result of the calculation is voltage distribution, density of electric current and losses, temperature distribution in the model at several time points and graph of temperature development over time.
Analysis of electrical and thermal effects during electroporation
Novotná, Veronika ; Richter, Aleš (referee) ; Hána,, Karel (referee) ; Červinka, Dalibor (advisor)
This dissertation thesis describes a phenomenon called electroporation. It is about its theoretical aspects as well as about modeling of processes in the tissue during electroporation. Further, it describes the technical design of two developed unique experimental generators of DC and AC pulses for electroporation purposes. It also includes a description of experiments which were done using discussed generators.

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