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Effect of resolution recovery on image quality in myocardial perfusion SPECT
Skibová, Daniela ; Šámal, Martin (advisor) ; Judas, Libor (referee) ; Zimák, Jaroslav (referee)
Objectives: Resolution recovery algorithms (IR-RR) were recently proposed as tools to improve quality of SPECT images through better resolution. The aim of the presented study was to investigate the effect of IR-RR on myocardial perfusion SPECT studies. Methods: Phantom and clinical studies were performed using SPECT-CT Infinia/Hawkeye (GE Healthcare). NEMA triple line phantom was scanned according to NEMA procedures. Cold sphere and cardiac phantom were scanned under clinical conditions (900 -angled detectors, 60 views and circular orbit) and reconstructed via IR-RR (Evolution for Cardiac, GE, 12 iterations and 10 subsets), OSEM (ordered subset expectation maximization, 2 iterations and 10 subsets) and FBP (filtered back projection). IR-RR and OSEM reconstructions were used with/without attenuation and scatter correction (ACSC). The effect of post-reconstruction filtering was evaluated. In clinical studies two data-sets were used (half-time and full-time). Conventional scan using full-time (20 sec per stress projection and 25 sec per rest projection) was reconstructed via FBP and IR-RR; half-time scan (10 sec stress, 12 sec rest studies) was reconstructed via IR-RR. End-diastolic volume (EDV), end-systolic volume (ESV) and left ventricular ejection fraction (EF) were calculated using two software...
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