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The electromigration methods and their use in the analysis of drugs.
Tučková, Dominika ; Tulková, Tereza (referee) ; Řezáčová, Veronika (advisor)
This bachelor thesis deals with the determination of septonex, effective component in medical agents, using capillary isotachophoresis. The main aim is optimization of this method for fast, sensitive and inexpensive determination of septonex. In bachelor thesis chemical and physical properties of septonex are introduced as well as its negative and positive properties, which can be used in medicine, and summary of possible methods of analysis. Further this thesis gathers information about drugs containing septonex and available on Czech market. Following chapters of the thesis summarize theory of electromigration methods, their principles, analytical devices and their use for septonex analysis. Finally, the thesis presents optimal conditions for analysis and results of determination of septonex in drug Septonex spray, which is available on Czech market, using capillary isotachophoresis. Content of determined septonex is compared to amount of septonex contained in this drug, which is declared by producer, in this thesis.
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The electromigration methods and their use in the analysis of drugs.
Tučková, Dominika ; Tulková, Tereza (referee) ; Řezáčová, Veronika (advisor)
This bachelor thesis deals with the determination of septonex, effective component in medical agents, using capillary isotachophoresis. The main aim is optimization of this method for fast, sensitive and inexpensive determination of septonex. In bachelor thesis chemical and physical properties of septonex are introduced as well as its negative and positive properties, which can be used in medicine, and summary of possible methods of analysis. Further this thesis gathers information about drugs containing septonex and available on Czech market. Following chapters of the thesis summarize theory of electromigration methods, their principles, analytical devices and their use for septonex analysis. Finally, the thesis presents optimal conditions for analysis and results of determination of septonex in drug Septonex spray, which is available on Czech market, using capillary isotachophoresis. Content of determined septonex is compared to amount of septonex contained in this drug, which is declared by producer, in this thesis.
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