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Noise dependence in PET liver image on patient's applied activity, weight and BMI
PEJŠKOVÁ, Veronika
The topic of this bachelor thesis is "Dependence of noise in the PET image of the liver on the applied activity, weight and BMI of the patient". Positron emission tomography (PET) is currently one of the most widely used examinations in the field of oncological diseases. The goal of the bachelor thesis is to monitor the noise in the PET image of the liver during positron emission tomography (PET) with FDG (fluorodeoxyglucose) depending on the applied activity, weight and BMI of the patient. Another goal of this work is to propose an alternative algorithm taking into account BMI in order to maintain the image quality and reduce the radiation exposure associated with the examination in addition to the existing algorithm for determining the activity of the applied amount of FDG based purely on patient weight. In connection with these goals, a hypothesis was developed where, taking into account the patient's BMI in determining the activity of the applied amount of FDG, the radiation exposure associated with the examination can be reduced while maintaining the noise level. In the introduction to this bachelor's thesis, I focused on a detailed description of the principle of the PET imaging method, it´s construction and everything associated with the PET imaging method. A substantial part of the theory of this work is occupied by information related to the quality of the PET image, especially the noise level. I also specified the individual radiopharmaceuticals used in the field of PET and I focused more attention on the radiopharmaceutical FDG, which is crucial for this work. Part of this bachelor thesis also deals with the applied activity and the elements related to it, is weight and BMI. In the last part of the bachelor thesis I focused on the description of the hybrid PET / CT method. The practical part was focused on quantitative research. For this research, it was first determined what parameters will need to be found for the processing of the practical part and then data were collected from patients examined by FDG PET / CT at the PET center in the Hospital of České Budějovice a.s. for the calendar year 2021. This data was then graphically plotted and finally used for analysis. In addition to the dependence of noise on patient weight, a representation of weight on patient BMI was created. The results of the practical part showed that the noise is affected by the applied activity, weight and BMI of the patient and based on further analysis, the initial hypothesis was confirmed. The final results of this work can be further used to optimize the examination protocol in the PET center of the Hospital of České Budějovice a.s.
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Complications during PET / CT examinations and frequency of occurration at the Department of Nuclear Medicine in České Budějovice Hospital, a.s.
HOUDKOVÁ, Tamara
This thesis is focused on complications at PET/CT examinations. The complications at these examinations are either processes which complicate the progress of examination within the meaning of affection of the quality of outcome efficiency or health complications as the linear after effect of PET/CT examination. In the first example it concerns of uncooperative patients with the excessive movements during examination or complicated venous acces for giving off intravenous screening substances. In the second example the most substantial complications are allergic reaction after delivery of jodinate contrasti substance. The object of this work was to follow complications at PET/CT examinations at the department of nuclear medicine of hostpital in České Budějovice, a.s. (here in after NEMČB), to do their analysis and in case of possibilities to suggest some systemic preventive measures. At the teoretical part of work I foccused on basic information about PET/CT device, the process of examination and all the facts related with it. At the description of particular complications I used my experience from the internship directly at the department of nuclear medicine at the NEMČB. Based on the inspection of actual state of affairs was set the hypothesis: 1. The most frequent complication at the PET/CT examinations are caused by the patients who do not cooperate. For the practical part was undertaken quantitative analysis. Data acquisition was done at the department of nuclear medicine of NEMČB by analysis of documentation of performed examinations in the term from January 2019 to June 2019. Datas were found out from application documents, the complications were then divided into four categories similarly teoretical part. Datas were statisticaly and graphicaly processed. The results of the work is possible to use as a basis for better quality of screening processes at the department of nuclear medicine and equally as the study material.
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