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Measurement of urine extinction in depending on ionizing radiation
RADOVÁ, Štěpánka
Urine Extinction Measurement in Dependence on Ionizing Radiation Dose Radiotherapeutic workplaces use ionizing radiation for treatment of tumorous but also some non-tumorous diseases. Medical staff of these departments is exposed to ionizing radiation on everyday basis and is thus endangered by harmful consequences. On the other hand a patient should be exposed to a neglect volume of ionizing radiation outside the radiated area. The conditions defining the means of protection for medical staff and patients are arranged by the law. So called dosimeters, are used for this purpose by medical staff, and urine might belong among them. This thesis deals with the issue whether urine could serve as a biological dosimeter that might be used either for continuous monitoring or for instantaneous determination of radiation dose. The next goal was to find out at what doses of ionizing radiation changes in urine extinction occur. The results show that urine provides qualitative but irreproducible values. Namely because of varying composition of urine and for presence of substances which, apart from water radiolysis, causing urine extinction changes, represent inhibitors or activators of these chemical reactions. This is why urine cannot serve as a biological dosimeter of radiation.

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