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Critical Factors of Implementation of Module APO to SAP System in the Chosen Manufacturing Company
Vetýška, Jan ; Skoupý, David (referee) ; Sodomka, Petr (advisor)
The thesis deals with the issue of the implementation of the corporate information system of the ERP category, specifically the introduction of the module of APO for SAP in the chosen manufacturing company. The work presents the theoretical fundamentals describing the basics of ERP along with available methodologies, the implementation of these systems. Also analyzes the frequent causes of delayed implementation projects and provides the basis for the search for the causes of the problems. In the next section it is made an overall analysis of the current state of the ERP system in the company. At the conclusion of this work are defined recommendations, which can be prevented critical factors and implementation could be completed according to the established timetable.
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Studium konformačních efektů vazby ligandu na proteinovou strukturu
Šefců, Oskar ; Novotný, Marian (advisor) ; Hexnerová, Rozálie (referee)
This bachelor thesis aims to provide a comprehensive overview of the effects of ligand binding on the 3D structure of proteins. The focus will be on examples where ligand binding causes a significant conformational change between the structure without the ligand (apo structure) and the structure with the ligand (holo-structure). The thesis will discuss various techniques used to determine the structural changes caused by ligand binding, including X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy. Furthermore, the thesis will provide insight into the structural and functional implications of ligand-induced conformational changes in proteins. Overall, this thesis will serve as a resource for understanding the role of ligand binding in modulating the 3D structure of proteins. Keywords: apo, holo, ligand, conformational change, IDP
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Critical Factors of Implementation of Module APO to SAP System in the Chosen Manufacturing Company
Vetýška, Jan ; Skoupý, David (referee) ; Sodomka, Petr (advisor)
The thesis deals with the issue of the implementation of the corporate information system of the ERP category, specifically the introduction of the module of APO for SAP in the chosen manufacturing company. The work presents the theoretical fundamentals describing the basics of ERP along with available methodologies, the implementation of these systems. Also analyzes the frequent causes of delayed implementation projects and provides the basis for the search for the causes of the problems. In the next section it is made an overall analysis of the current state of the ERP system in the company. At the conclusion of this work are defined recommendations, which can be prevented critical factors and implementation could be completed according to the established timetable.
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