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National Repository of Grey Literature

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5-(Pyren-1-yl)uracil UNA monomers: Synthesis, hybridization studies and i-motif stability Perlíková, Pavla ; Pedersen, E. B. ; Wengel, J. We have used direct conjugation of a pyrene moiety to a uracil base in synthesis of novel pyrene-modified UNA building blocks. Oligonucleotides with bulge-incorporated pyrene-modified UNA monomers showed increased duplex thermal stability, whereas destabilizing effect was observed in fully matched duplexes and in i-motifs. Detailed record

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