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Growth and bone mineral density in girls with Turner syndrome
Matysková, Jana ; Zemková, Daniela (advisor) ; Koloušková, Stanislava (referee)
Turner syndrome is disease caused by monosomy or other abnormalities of chromosome X. This syndrome affects exclusively females and is characterized by growth retardation leading to short final stature, gonadal dysgenesis and other abnormalities of different organs. This work describes current etiological and diagnostic aspects of Turner syndrome, especially growth failure and low bone mineral density as a factor contributing to increased bone fragility.
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Effect of celiac disease on growth and bone density.
Ondráčková, Markéta ; Zemková, Daniela (advisor) ; Tůma, Jan (referee)
Celiac disease is a chronic autoimmune disease of the small intestine caused by intolerance to gluten. The disease is characterized by impairment of intestinal mucosa, it is associated with malabsorption and maldigestion. The main symptoms are stomach pain, diarrhea, anemia, failure to thrive. Recently, the number of patients with atypical symptoms and a completely asymptomatic form of the disease increases. Prevalence of the disease in Europe is 1 %. The aim of this paper is to describe how celiac disease affects the status of bone tissue and what is its impact on growth in children.
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Study of somatic traits of linear proporcionality in boys at the age of 11 to 14 years.
Němcová, Kateřina ; Sedlak, Petr (advisor) ; Zemková, Daniela (referee)
This study brings the information on linear body proportionality of pubescent boys. The body linear proportionality was validated by using the SD scores gained from the measured data and by validating the individual proportionality with help of natural Percal indices. Each child was considered according to his biological maturity by using KEI index. For rating of the growth of individual and his proportionality, the compliance of KEI index and the difference of height and chronological age were validated. The considering of those biological trends made it possible to separate the individuals with possible physiological variant of normal growth from the individuals with suspective growth pathology. The set included 346 boys in the age of 10-14 years, after replacing of disproportional individuals from the study. For evaluation of changes in the linear body proportionality the linear somatic markers with high degree of accuracy and reliability of measurement were chosen and the descriptional statistics were set to these parameters and to their indices. Comparing with reference sets the changes in proportional relations in year and half-year cathegories were described. Descriptive statistics of subischial length to sitting height index and arm span to body height index are not part of the referencial standard...
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Selected auxological aspects of autism in children
Blovská, Petra ; Zemková, Daniela (referee) ; Krásničanová, Hana (advisor)
5 Abstract Introduction. Autism is a severe developmental disorder with a neurobiological basis, whose etiology has yet to be fully clarified. It is a multi-factorial illness, influenced largely by genetic predispositions as well as external factors. The goal of this paper was to determine basic auxological attributes of male autistic patients with incomplete growth and to describe how this complex disorder of a developing brain alters somatic development of these severely ill individuals. Data and Method. The study is founded on transversal data of 69 boys from the whole of Czech Republic with the diagnosis child autism and age from 3,3 to 13,4 years. All patients were examined at the Department of Clinical Anthropology of the Pediatric Clinic, Motol University Hospital, 2nd Faculty of Medicine, Charles University, in the period from 2000 to 2008. Attributes that objectify state of growth, state of nourishment and cranium size were measured. A part of the study was also the evaluation of the influence of heredity on body height and cranium size. The collected auxological data were converted to SDS, the results were tested by means of a one-sample t-test. Results. Boys with autism have significantly decreased body height (x̄ = −0,36 ± 1,12, p = 0,010), midparental height in accordance with standards and...
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