National Repository of Grey Literature 9 records found  Search took 0.00 seconds. 
Heme catabolic pathway in pathogenesis of liver diseases
Váňová, Kateřina ; Muchová, Lucie (advisor) ; Brůha, Radan (referee) ; Neužil, Jiří (referee)
This thesis focuses on the role of heme catabolic pathway in the pathogenesis of selected liver diseases. The aim was to clarify if the modulation of heme oxygenase (Hmox) and its catabolic products - especially carbon monoxide (CO) and bilirubin - affected the development and progression of liver diseases, focusing on inflammatory and cholestatic pathways. Firstly, we discovered that the induction of hmox1 prevented hepatocellular damage in endotoxin-induced inflammation. Furthermore, administration of CO in vivo in early-phase of endotoxin-induced cholestasis decreased the inflammatory cytokine production in the liver and simultaneously prevented downregulatory effect of cytokines on hepatocyte transporters resulting in hepatoprotection. For the first time, we characterized in vivo tissue distribution and elimination of inhaled CO in rats. In vitro experiments and the model of extrahepatic cholestasis revealed the significant role of intracellular bilirubin in hepatocellular protection against oxidative damage which accompanies cholestatic disorders. Last but not least, hmox1 induction by heme increased hepatocyte transporters expression and subsequently stimulated bile flow participating in conferring protection against estrogen-induced cholestasis. Presented results demonstrate that the heme...
Woman and her body
Váňová, Kateřina ; Hogenová, Anna (advisor) ; Hrabinec, Jiří (referee)
v angličtině This master thesis is about woman and her body. If a woman wish to be healthy, her soul and body should be in harmony. If she follows her own way, she is in harmony with society, she has time for relaxing and takes care for her soul she is happy. Society at this time is trying to separate soul and body. But when we are lost we can find the truth and ourselves. We can take care of our soul in this ways: relaxing, meditation, movement. When we are moving, soul is in harmony with a body. Every woman has shapes of her body from her forefathers and she should appreciate it.
Higher Education Graduates in the Labour Market
Váňová, Kateřina ; Rychtaříková, Jitka (advisor) ; Kraus, Jaroslav (referee)
The aim of my final master thesis is to describe the situation about higher education graduates and their position on the labour market in the Czech Republic. I am especially observing the employment and unemployment situation of people who have completed higher education. Due to the rapid increase in their number, I consider the topic to date. For assessing the whole situation first I characterize the educational situation in the Czech Republic. I focus on the educational structure of the population by age, gender and region. I am using mainly data from the Labour Force Survey, averages for the year 2014. Furthermore I briefly describe higher education students and recent graduates. Finally, I try to link these two parts with part of the labour market. To track the position of educated people like this I use descriptive methods and analytical methods. I deal with the influence of education on time spent on the labour market. Based on the tables of the economic activity I estimate the life expectancy of activity life by educational attainment. For this I am using the educational structure of the population from the Labour Force Survey and data on the number of deaths. In the final analytical part of my work I observe with the help of logistic regression and statistical program SAS the odds ratios...
Heme catabolic pathway in pathogenesis of liver diseases
Váňová, Kateřina ; Muchová, Lucie (advisor) ; Brůha, Radan (referee) ; Neužil, Jiří (referee)
This thesis focuses on the role of heme catabolic pathway in the pathogenesis of selected liver diseases. The aim was to clarify if the modulation of heme oxygenase (Hmox) and its catabolic products - especially carbon monoxide (CO) and bilirubin - affected the development and progression of liver diseases, focusing on inflammatory and cholestatic pathways. Firstly, we discovered that the induction of hmox1 prevented hepatocellular damage in endotoxin-induced inflammation. Furthermore, administration of CO in vivo in early-phase of endotoxin-induced cholestasis decreased the inflammatory cytokine production in the liver and simultaneously prevented downregulatory effect of cytokines on hepatocyte transporters resulting in hepatoprotection. For the first time, we characterized in vivo tissue distribution and elimination of inhaled CO in rats. In vitro experiments and the model of extrahepatic cholestasis revealed the significant role of intracellular bilirubin in hepatocellular protection against oxidative damage which accompanies cholestatic disorders. Last but not least, hmox1 induction by heme increased hepatocyte transporters expression and subsequently stimulated bile flow participating in conferring protection against estrogen-induced cholestasis. Presented results demonstrate that the heme...
Professional Image of a Druggist and its Impact on Customer Satisfaction
Váňová, Kateřina ; Macurová, Jana (referee) ; Konečná, Zdeňka (advisor)
Presenting principles of forming of professional´s image and its influence on business success and customers is the purpose of this bachelor´s thesis. It is focused on identification of personality profile of successful druggist including recommendation of competent companies in the sphere of specialized training.
Evaluation of Company Performance
Zachovalová, Lenka ; Váňová, Kateřina (referee) ; Mašterová, Lucie (advisor)
This master´s thesis is focused on the evalution of company Lázně Poděbrady, a.s. in years 2010 – 2012. The theoretical part describes an issue of company performance measurement and the practical part contains evaluating the performance the chosen company. The last part includes suitable suggestions to ensure the continued performance of the company.
Marketing Research of Customer Satisfaction
Váňová, Kateřina ; Macurová, Jana (referee) ; Šimberová, Iveta (advisor)
This master´s thesis is focused on the marketing research of customer satisfaction. It provides the theoretical knowledge concerning the field of marketing research, including its practical application in the company and presents the results of the analysis of obtained data. At the same time it proposes improvement suggestions of existing situation.
Personal deixis in Spanish and Czech: a comparison of web pages of travel agencies
VÁŇOVÁ, Kateřina
The aim of this bachelor thesis is to briefly present the issue of personal deixis in the Czech and Spanish languages. The second aim is to analyse this personal deixis on the websites of Czech and Spanish travel companies. The thesis is divided into two main parts: theoretical and practical. The theoretical part of the work is focused on defining the theoretical concepts in the deictic field. The practical part contains an analysis of the web pages of Czech and Spanish travel companies, a comparison of the assumption and the result of the analysis and a summary of the differences between the results of the Czech and Spanish web pages analysis. The bachelor thesis begins with an introduction, ends with a conclusion and a résumé in the Spanish language completes the work.
The United States Census
Váňová, Kateřina ; Langhamrová, Jitka (advisor) ; Kozelský, Tomáš (referee)
The main objective of this thesis is to make a clear picture about the U.S. Census. The purpose is in focusing on its reasons, process, history and results. The chapters have a theoretical character. The first chapter deals with the reasons of the census. These are closely connected with the creation of the census, so the second chapter is about the census history. After that, the proces of the current census is desribed. First the method, that means, how the census is realized and then who is involved. The next part is about the data collection. The thesis also include informations about the census form and the paid campaign. The last chapter includes the main results of the census.

See also: similar author names
4 VÁŇOVÁ, Kristýna
3 Váňová, Karolína
9 Váňová, Kateřina
2 Váňová, Klára
4 Váňová, Kristýna
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