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Molecular cytogenetics of selected actinopterygian fishes: insight from repetitive sequences to whole genome analyses
Majtánová, Zuzana ; Symonová, Radka (advisor) ; Marec, František (referee) ; Šťáhlavský, František (referee)
Actinopterygian fishes exhibit the greatest taxonomical diversity of all vertebrates, making this group attractive to address numerous evolutionary questions. The role of molecular cytogenetics and cytogenomics further increase because recent advances in these fields provide more comprehensive view of fish genome organization and evolutionary dynamics, responsible for this amazing diversity. My Thesis investigates the genome organization of selected fish lineages, namely basal lineages of Actinopterygians (Lepisosteidae and Amiidae) and Teleosts (Pantodontidae), together with "modern" fishes Cobitidae and Coregonidae. I have integrated conventional and molecular cytogenetic techniques together with phylogenetic and statistical approaches. Publications included into the Thesis describe e.g. the cytogenetic variability and dynamics in closely related fish species of the genus Coregonus and the impact of repetitive sequences on the ecological speciation. In contrast to the recent cytotaxonomical diversity of Coregonids, we have detected a karyotype stability associated with asexual reproduction in spined loaches of the genus Cobitis. In the subsequent publication, we describe a surprising AT/GC genome organization in gars (Atractosteus and Lepisosteus) and summarize the knowledge of genome...

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