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Determining the plasticity of microcrystalline celulose
Skálová, Marie ; Řehula, Milan (advisor) ; Špaček, Vladimír (referee)
Important properte of pressed (compacting) materials is their energy and plasticity. For their calculation is used several methods. One of values elasticity or plasticity energy from record power-line, in another metod is used elastic recovery, which is used for calculation of Young's elastic modul and the third one value stress relaxation of tenseness. In this analyze we can get parameters as FminA, FminB, Fpl and also characterization of ralation dependence compression in the time. In this dissertation is valueted one of the most common excipient microcrystaline celulose by all these methods. Basic characteristic is Young's elastic modul ,which is 253,794MPa and total plasticity is 995,48. We can say, that values of total plasticity means good compressible material and that plasticity increases with increasing of total plasticity.
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Viscoelastic properties of microcrystalline cellulose of Avicel PH 200
Skálová, Marie ; Řehula, Milan (advisor) ; Špaček, Vladimír (referee)
In this dissertation the viscoelasticity of the most common excipient microcrystaline celulose was valuated and viscoelasticite parametres were compared to three substances. Viscoelasticity was valuated by two methods..The first method is Creep test. In this analyze the compression force is constant and hold for 180s. During this time height of the tablet was lowered. The diffrences of tablet height was noted and used for calculation in Crčel test. Parameters of elasticity got by this method are FCT1,FCT2 and parameters of plasticity are PCT1,FP. When the parameters of elasticity increase the elasticity decrease. When the parameter FP increases the plasticity increases too. The higher the value of PCT1 is the lower is the plasticity. Stress relaxation is the second method. In this analyze hight of tablet is constant and decline compression force is recorded. In this analyze we noted the decline for 180 sec. In this way we get parameters of elasticity ESR1, ESR2, ESR3 and parameters of plasticity PSR1, PSR2, PSR3. The plasticity increases when parameter P increases. Comparing three substances the elasticity increases in-line Emcompress, Avicel, Flowlac and the elasticity decreases in-line Emcompress, Avicel, Flowlac.
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Applications of Groebner bases
Skalová, Marie ; Příhoda, Pavel (advisor) ; Šťovíček, Jan (referee)
Groebner bases are useful tool of algebraic geometry for geometry proving. In the thesis we are presenting an automatic geometric theorem proving method in two vari- ants. Firstly, a variant based on the book D. Cox, J. Little, D. O'Shea Ideals, varieties, and algorithms. An introduction to computational algebraic geometry and commutative algebra and secondly a variant based on the book D. Stanovský, L. Barto, Počítačová algebra. We summarize theory, which is necessary for deduction of the method, then the- ory, which is necessary for definition of Groebner base and theorem about her properties. The thesis is including solved problems used for motivate several steps in method and solved exercises from already mentioned book by D. Cox, J. Little, D. O'Shea, some of them are solved by both variants. There is also own proof of decomposition of an affine variety in chapter 2. 1
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Determining the plasticity of microcrystalline celulose
Skálová, Marie ; Řehula, Milan (advisor) ; Špaček, Vladimír (referee)
Important properte of pressed (compacting) materials is their energy and plasticity. For their calculation is used several methods. One of values elasticity or plasticity energy from record power-line, in another metod is used elastic recovery, which is used for calculation of Young's elastic modul and the third one value stress relaxation of tenseness. In this analyze we can get parameters as FminA, FminB, Fpl and also characterization of ralation dependence compression in the time. In this dissertation is valueted one of the most common excipient microcrystaline celulose by all these methods. Basic characteristic is Young's elastic modul ,which is 253,794MPa and total plasticity is 995,48. We can say, that values of total plasticity means good compressible material and that plasticity increases with increasing of total plasticity.
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Viscoelastic properties of microcrystalline cellulose of Avicel PH 200
Skálová, Marie ; Řehula, Milan (advisor) ; Špaček, Vladimír (referee)
In this dissertation the viscoelasticity of the most common excipient microcrystaline celulose was valuated and viscoelasticite parametres were compared to three substances. Viscoelasticity was valuated by two methods..The first method is Creep test. In this analyze the compression force is constant and hold for 180s. During this time height of the tablet was lowered. The diffrences of tablet height was noted and used for calculation in Crčel test. Parameters of elasticity got by this method are FCT1,FCT2 and parameters of plasticity are PCT1,FP. When the parameters of elasticity increase the elasticity decrease. When the parameter FP increases the plasticity increases too. The higher the value of PCT1 is the lower is the plasticity. Stress relaxation is the second method. In this analyze hight of tablet is constant and decline compression force is recorded. In this analyze we noted the decline for 180 sec. In this way we get parameters of elasticity ESR1, ESR2, ESR3 and parameters of plasticity PSR1, PSR2, PSR3. The plasticity increases when parameter P increases. Comparing three substances the elasticity increases in-line Emcompress, Avicel, Flowlac and the elasticity decreases in-line Emcompress, Avicel, Flowlac.
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