National Repository of Grey Literature 13 records found  1 - 10next  jump to record: Search took 0.01 seconds. 
Functional encryption for quadratic functions
Sýkora, Josef ; Žemlička, Jan (advisor) ; Růžička, Pavel (referee)
In this thesis we will be studying functional encryption for quadratic functions. We want to encrypt a message, in form of a vector, z to a plaintext ct and create a secret key skf for a quadratic function f, which will allow us to decrypt ct to f(z), while the ct and skf will not leak any information about z. We will introduce one concrete design. The aim of this thesis will be the preparation of necessary preliminaries, which will allow us to describe the design, and to verify correctness of the algorithms. We will describe Arithmetic Branching Programs. Such objects will help us represent function f. Furthermore, we will introduce Garbling and Partial Garbling schemes. Those will allow us to "randomize"a part of the algorithm. We will also specify an encryption algorithm for linear transformation and use it to describe the main encryption algorithm for quadratic functions. 1
Autoimmune thyroiditis in children and the role of simultaneous Helicobacter pylori infection
Pomahačová, Renata ; Sýkora, Josef (advisor) ; Hníková, Olga (referee) ; Kalvachová, Božena (referee)
1. Summary The first aim of our study was to find out the present occurence of H. pylori infection in a group of children with juvenile lymphocytic thyroiditis (JLT) and to compare with the prevalence of this infection in a group of healthy children of the same age. The group of patients with JLT included 199 children (range 0-18 years). H. pylori infection was confirmed in 15 patients (7,5%) by a non-invasive diagnostic test of H. pylori antigen positivity in stools by the ELISA test using monoclonal antibodies (Amplified IDEIQA HpStAR ELISA, DakoCytomation, Glostrup, Denmark). This H.pylori positive group included 14 girls and 1 boy aged 11,2 ±2,3. 6 children had hypofunction of the thyroid gland, in 3 children was established the atrophic form of the thyroiditis with severe hypothyroidism with presence of myxoedema, the other children suffered from the hypertrophic form of the thyroiditis. 7 subjects underwent gastroscopy which confirmed chronic active gastritis. Only 3 children had gastrointestinal symptoms caused by H. pylori infection, the other children were asymptomatic. This finding confirms common information about asymptomatic development of H. pylori infection in children in 90% of cases. The control group included 1545 asymptomatic healthy children in range of 0-15 years of the same geographic...
Impact of the Gastrointestinal System on Metabolic Control in Children with Type 1 Diabetes Mellitus - Gut Peptide Hormones
Huml, Michal ; Sýkora, Josef (advisor) ; Dědek, Petr (referee) ; Rušavý, Zdeněk (referee)
Our objective was to evaluate plasma levels of gut hormones and hormones associated with glucose metabolism in children with type 1 diabetes mellitus (T1DM), and to correlate plasma concentrations of gut hormones with blood biochemistry, markers of metabolic control and anthropometric parameters. A multiplex assay kit (LINCOplex® ) was used for the determina- tion of postprandial plasma levels of specific gut peptide hormones. Amylin, glucose- dependent insulinotropic polypeptide (GIP), active glucagon-like peptide 1 (GLP-1), active ghrelin, insulin, leptin, pancreatic polypeptide (PP), and polypeptide YY (PYY) were assessed prospectively in 55 subjects including 19 T1DM children (mean age: 13.4 years) and 21 healthy reference controls (mean age: 13. 4 years) and 15 patients with functional abdominal pain (FAP) (mean age: 10.5 years). In total, 440 plasma hormones samples were assessed in 55 patients. Entered data were examined using a non-parametric Wilcoxon's test. Further- more, statistically significant correlations were assessed by stepwise regression analysis. Our study demonstrated that the determination of specific postprandial gut hormones with the multiplex assay kit (LINCOplex® ) was highly efficient. Not only was a small amount of plasma sample (25µl) required for analysis, but also a...
Home confinement
Sýkora, Josef ; Jelínek, Jiří (advisor) ; Tlapák Navrátilová, Jana (referee)
195 Home confinement Abstract The inexorable rise of inmates, coupled with disappointingly high rate of reccurence of crime, has refocused attention on finding alternatives to imprisonment regarding criminal sanctions permitted by the new Penal Code of the Czech Republic which came into force on 1 January 2010. This thesis was aimed at dealing with a comprehensive analysis of home confinement. The application of legal doctrine is of fundamental relevance to house arrest related to de lege lata and de lege ferenda provisions. The concept of home confinement as an alternative to criminal incarceration to provide inmates the opportunity and privilege of living at home is associated with the principles of punishment and reducing overcrowding at the jail. This sanction, however, has not yet anchored in the context of penal sanctions. The main reason is the failure to optimally connect real legislation, application practice, the state's interest and a well- functioning infrastructure. The current de lege lata editing in the context of the application practice is considered to be in conformity with advanced foreign legal systems. Nevertheless, we must insist on the fact that currently our situation is far from reaching the desirable legislative stability related to house arrest, despite the current valid...
Cardiovascular Risks in Chronic Airway Disease in Childhood
Kreslová, Marcela ; Sýkora, Josef (advisor) ; Fila, Libor (referee) ; Kopřiva, František (referee)
1 Cardiovascular risks in chronic airway disease in childhood The aim of this thesis was to evaluate cardiovascular risk by using a combined diagnostic approach by measuring RHI and specific biochemical markers in patients with chronic respiratory disease, where we could assume a possible risk of CVD. A total of 119 probands were examined, including 22 patients with cystic fibrosis (CF) and 52 asthma patients. We evaluated RHI using a new plethysmographic method that has a number of advantages over the ultrasonographic methods used in other studies, including non-invasiveness, high sensitivity, low biological variability and objectivity due to automatic processing. Of the biochemical parameters, we measured 4 biomarkers in relation to endothelial dysfunction (ED): hsCRP, ADMA, E-selectin, and VCAM-1. We compared RHI and biomarkers in CF and asthma patients with healthy controls and sought mutual correlations. We did not prove a statistically significant difference in RHI between the test groups with CF children but we confirmed the decreasing trend of RHI since adolescence and significantly lower RHI values in CF adults, confirming the progressive development of atherogenesis and worsening of ED with age. Biochemical parameters showed significantly higher levels of hsCRP, sVCAM-1 and E-selectin in CF...
The evaluation of calprotectin levels in the stool of paediatric patients and helathy children in the Czech republic
Siala, Konrad Karim ; Sýkora, Josef (advisor) ; Houšťková, Hana (referee) ; Volf, Vladimír (referee)
The work deals with the evaluation Calprotectin levels in healthy children and pediatric patients in the Czech Republic.
Home confinement
Sýkora, Josef ; Jelínek, Jiří (advisor) ; Tlapák Navrátilová, Jana (referee)
195 Home confinement Abstract The inexorable rise of inmates, coupled with disappointingly high rate of reccurence of crime, has refocused attention on finding alternatives to imprisonment regarding criminal sanctions permitted by the new Penal Code of the Czech Republic which came into force on 1 January 2010. This thesis was aimed at dealing with a comprehensive analysis of home confinement. The application of legal doctrine is of fundamental relevance to house arrest related to de lege lata and de lege ferenda provisions. The concept of home confinement as an alternative to criminal incarceration to provide inmates the opportunity and privilege of living at home is associated with the principles of punishment and reducing overcrowding at the jail. This sanction, however, has not yet anchored in the context of penal sanctions. The main reason is the failure to optimally connect real legislation, application practice, the state's interest and a well- functioning infrastructure. The current de lege lata editing in the context of the application practice is considered to be in conformity with advanced foreign legal systems. Nevertheless, we must insist on the fact that currently our situation is far from reaching the desirable legislative stability related to house arrest, despite the current valid...
Impact of the Gastrointestinal System on Metabolic Control in Children with Type 1 Diabetes Mellitus - Gut Peptide Hormones
Huml, Michal ; Sýkora, Josef (advisor) ; Dědek, Petr (referee) ; Rušavý, Zdeněk (referee)
Our objective was to evaluate plasma levels of gut hormones and hormones associated with glucose metabolism in children with type 1 diabetes mellitus (T1DM), and to correlate plasma concentrations of gut hormones with blood biochemistry, markers of metabolic control and anthropometric parameters. A multiplex assay kit (LINCOplex® ) was used for the determina- tion of postprandial plasma levels of specific gut peptide hormones. Amylin, glucose- dependent insulinotropic polypeptide (GIP), active glucagon-like peptide 1 (GLP-1), active ghrelin, insulin, leptin, pancreatic polypeptide (PP), and polypeptide YY (PYY) were assessed prospectively in 55 subjects including 19 T1DM children (mean age: 13.4 years) and 21 healthy reference controls (mean age: 13. 4 years) and 15 patients with functional abdominal pain (FAP) (mean age: 10.5 years). In total, 440 plasma hormones samples were assessed in 55 patients. Entered data were examined using a non-parametric Wilcoxon's test. Further- more, statistically significant correlations were assessed by stepwise regression analysis. Our study demonstrated that the determination of specific postprandial gut hormones with the multiplex assay kit (LINCOplex® ) was highly efficient. Not only was a small amount of plasma sample (25µl) required for analysis, but also a...
Immunesuppressive treatment of Crohn's disease in children
Malý, Jan ; Pozler, Oldřich (advisor) ; Doležel, Zdeněk (referee) ; Sýkora, Josef (referee)
Crohn disease (CD) treatment in children doesn't differ from adults today. The main role in management of disease play systemic corticosteroids (CS) and immunesupressants. Aims: 1) evaluate efficacy and hepatotoxicity of 6-thioguanine (6-TG) on mice model of experimental colitis. 2) evaluate time to steady state of 6-thioguanine nucleotides after azathioprine (AZA) treatment initiation in children with inflammatory bowel disease (IBD). 3) evaluate dose (incl. cumulative dose) of CS applied through the first year after diagnosis according to disease activity. 4) AZA steroid sparing effect analysis in week 52 of follow up. Methods: 1) Dextran sodium sulfate colitis was induced in 50 mice (BALb/c F) for 9 days, treatment with placebo, AZA and 6-TG started at once. Study was terminated on day 14. 2) inclusion criteria: new IBD diagnosis, AZA treatment. Steady state analysis was performed by high performance liquid chromatography. 3-4) inclusion criteria: age 0-19, CD (according to Porto criteria), prospective disease activity assessment, follow-up at least 52 weeks. Results: 1) 6-TG is highly effective in acute phase of experimental colitis (p<0.01), liver toxicity was not ascertained. 2) Median time to steady state of 6-TG nucleotides was 29.7 days (8.4-156), 75.4 days represented time to steady state...
Autoimmune thyroiditis in children and the role of simultaneous Helicobacter pylori infection
Pomahačová, Renata ; Sýkora, Josef (advisor) ; Hníková, Olga (referee) ; Kalvachová, Božena (referee)
1. Summary The first aim of our study was to find out the present occurence of H. pylori infection in a group of children with juvenile lymphocytic thyroiditis (JLT) and to compare with the prevalence of this infection in a group of healthy children of the same age. The group of patients with JLT included 199 children (range 0-18 years). H. pylori infection was confirmed in 15 patients (7,5%) by a non-invasive diagnostic test of H. pylori antigen positivity in stools by the ELISA test using monoclonal antibodies (Amplified IDEIQA HpStAR ELISA, DakoCytomation, Glostrup, Denmark). This H.pylori positive group included 14 girls and 1 boy aged 11,2 ±2,3. 6 children had hypofunction of the thyroid gland, in 3 children was established the atrophic form of the thyroiditis with severe hypothyroidism with presence of myxoedema, the other children suffered from the hypertrophic form of the thyroiditis. 7 subjects underwent gastroscopy which confirmed chronic active gastritis. Only 3 children had gastrointestinal symptoms caused by H. pylori infection, the other children were asymptomatic. This finding confirms common information about asymptomatic development of H. pylori infection in children in 90% of cases. The control group included 1545 asymptomatic healthy children in range of 0-15 years of the same geographic...

National Repository of Grey Literature : 13 records found   1 - 10next  jump to record:
See also: similar author names
36 Sykora, Jan
9 Sýkora, Jakub
36 Sýkora, Jan
6 Sýkora, Jaroslav
11 Sýkora, Jiří
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