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Association Between Echocardiogrtaphic Markers and Glomerular and Tubular Kidney Functions in Cardiologic Patients
Opatrný, Jan ; Matoušovic, Karel (advisor) ; Dusilová Sulková, Sylvie (referee) ; Pařenica, Jiří (referee)
A close relation between the kidneys and the heart functions is a long lasting clinical experience. In the second half of the XXth century, many studies documented a role of the kidneys in blood pressure regulation. Since the beginning of the XXI century, many findings have highlighted a role of a damaged kidney function as a risk factor for the heart injury. A close link between the heart and kidney functions is mediated by many common pathophysiologic mechanisms. It is surprising, that terms cardio-renal and renocardiac syndromes have got in a common awareness of clinicians only in the last 15 years. Some links between echocardiopgraphic signs of the systolic and diastolic heart dysfunction and the glomerular kidney function has already been described. Relations between the cardiorenal syndrome and echocardiographic findings versus the renal concentrating capacity are unknown. It is well established, that even mild renal insufficiency increases the mortality risk in ischemic heart disease patients. A question arises, if only a transient decrease of the renal function influences a mortality risk in ischemic heart disease patients. The aim of our study was to find out: A) The associations between the echocardiographic signs of systolic and diastolic heart dysfunction, the eGFR and the kidney...

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2 Opatrný, Jiří
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