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Use of NMR in structural analysis
Novák, Zdeněk ; Kuneš, Jiří (advisor) ; Špulák, Marcel (referee)
This Diploma work is consecrated to structure determination of unknown substances. The Department of Pharmaceutical Botany and Ecology, Faculty of Pharmacy in Hradec Králové isolated number of alkaloids from three plants: Zanthoxylum nitidum (Roxb.) DC (Rutaceae), Corydalis cava (L.) Schw. et Koerte (Fumariaceae) and Zephyranthes robusta Baker (Amaryllidaceae). Some of thath alkaloids were analyzed in Laboratory of structure and interactions. The goal of this project was to determinate the structure of three unknown product, using NMR. NMR experiments (1 H NMR, 13 C NMR, ghmqfcops, ghsqc, ghmbc) were necessary to reveal the structure of unknown compounds.
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The correlation of intracranial pressure and next investigative parameters at the cerebral contusion
Škúci, Ivan ; Choc, Milan (advisor) ; Novák, Zdeněk (referee) ; Smrčka, Martin (referee)
Patients with a brain injury must overcome a central neurological insult and a systematic metabolic response. The systematic response includes hypermetabolism, hypercatabolism, altered vascular permeability, increased hormone and cytokine release, altered gastric emptying, altered mineral metabolism and altered immune status. This response may initiate mechanisms which lead to secondary brain injury and may adversely affect the function of other organs. Last two decades have improved our knowledge of pathophysiology in patients with primary and secondary brain injury including traumatic contusions. In a moment of injury, primary brain injury which is traumatic contusion can not be therapeutically prevented it can only have a preventive effect. Secondary brain injury can be therapeutically affected although both types of injuries have common pathophysiological signs of disturbed metabolism on cells and subcellular level. Research methods based on molecular biology opens a new zone of research reaction of central neurological system for trauma or ischemia with effort to get involved immediately at the beginning of developing adverse pathophysiological cascade leading to a death of neurotic cell. The brain contusion is a primary centre of brain injury with anatomic changes which can be graphically proved. In...
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Business Plan, Establishment of a New Company
Koukal, David ; Novák, Zdeněk (referee) ; Rompotl, Jaroslav (advisor)
The bachelors thesis describes the establishment of a new distribution company that will deal with the distribution of the company, which operates in automotive industry. The thesis analyzes both, the internal and external enviroment of founded distribution company VINTECH-EU Ltd. Thanks to the analysis was compiled such a business plan that includes expected future vision of partners, the current state of the market and reflects the knowledge that I have acquired during my studies.
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Business Plan for the Development of the Company
Tylich, Zbyněk ; Novák, Zdeněk (referee) ; Rompotl, Jaroslav (advisor)
This bachelor thesis focuses on the creation of business development plan of company Sezako Přerov Ltd. Theoretical section contains information about creating business plan. The thesis also contains an analysis of the current situation and on the basis of proposal to solution. On finding opportunities in operating activities and consecutive devising a plan that would help to increase profits, to stabilize and increase market share and consolidate business position of the company.
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Business Plan
Šenkýřová, Iva ; Novák, Zdeněk (referee) ; Rompotl, Jaroslav (advisor)
This bachoral thesis is focused on business plan composition as a future source for the company Pneuservis Holíková business development. It consists of the business plan theoretical description continued by the current company status evaluation and is closed up by the most advantageous option choice proposal.
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Business Plan
Pártlová, Monika ; Novák, Zdeněk (referee) ; Rompotl, Jaroslav (advisor)
This bachelor thesis is focused on evaluating the effectiveness of a business plan (the increase in sales of specialized wooden furniture), obtaining a higher market share in the market and expanding the portfolio of new products and services. Recommendations how to improve the current situation of the company have been based on the results of analyses and their evaluation.
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Business Plan
Zavoralová, Štěpánka ; Novák, Zdeněk (referee) ; Rompotl, Jaroslav (advisor)
In the thesis I will deal with the processing of a business plan. On the basis of theoretical knowledge will build a private kindergarten Minnie focused on the English language, which will be located in the center of Hradec Králové.
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