National Repository of Grey Literature 39 records found  beginprevious21 - 30next  jump to record: Search took 0.00 seconds. 
Type II secretion system in gram negative bacteria.
Klápšťová, Veronika ; Doležal, Pavel (advisor) ; Mach, Jan (referee)
This thesis describes the structure and the assembly of the type II secretion system which is found in some gram negative bacteria such as Vibrio cholerae, Pseudomonas aeruginosa, Legionella pneumophila or Klebsiella oxytoca and which transports their exoproteins across the outer membrane. The thesis also presents some important substrates translocated by this system - toxins, enzymes and proteins involved in bacterial metabolism or motility - and hypothetical mechanism of the secretion. Conclusion is focused on the discovery of the secretion system in mitochondria of some protists and its importance for the research of the evolution of eukaryotic organisms.
Advances in treatment of human trypanosomiasis
Novotná, Kristýna Klára ; Mach, Jan (advisor) ; Grekov, Igor (referee)
Sleeping sickness is a human disease found in sub-saharan Africa, and is caused by a parasitic protozoan Trypanosoma brucei. Trypanosoma brucei species infects various mammals, however, only Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense subspecies are resistant to trypanolytic factors found in human blood serum. This work briefly summarizes known operating mechanisms of trypanolytic factors and resistance mechanisms of trypanosomes to these factors. The work covers mainly description and summarization of current diagnostic methods of sleeping sickness and used trypanocidal drugs. Majority of introduced methods shows high levels of sensitivity and specificity, however, for poor, disease affected areas they are often way too expensive. Prescribed drugs are expensive as well, and what's more, they are often ineffective against both subspecies and have severe side effects. Last part of the work is dedicated to potential development of new medicaments.
Management, Retrieval and Access to Electronic Theses and Dissertations
Mach, Jan ; Bratková, Eva (advisor) ; Strossa, Petr (referee) ; Souček, Martin (referee)
The dissertation is devoted to analysis of current practice and trends in providing repositories of electronic theses and dissertation (ETDs) in terms of their management, searching and dissemination. The first part presents terminology and the current state of access to ETDs in Czech and foreign repositories and includes results of a survey of the state of access to ETDs in the Czech Republic which was completed in 2014 by all public universities. In the second part, a metadata standard is presented, particularly the possibility of mapping EVSKP-MS metadata elements to other metadata formats and utilization within the OAI-PMH protocol. The issue of access to ETDs is dealt with further in terms of metrics for an evaluation of usage of distributed ETDs. Searching for ETDs is also described in case studies as are recommendations for public tenders for a discovery service and for creating an ETD metadata search server and an associated user interface with faceted search. The final part of the thesis focuses on the issue of plagiarism. This incorporates a presentation and analysis of the most important plagiarism detection systems and a case study of the development of the portal Validátor VŠE to provide access to results of document analysis.
Physical Phenomenon as a Creative Method in Architecture
Buryová, Tereza ; Mach, Jan (referee) ; Kristek,, Jan (advisor)
Cellular_ polar research station Antarctica is the driest, the busiest and most extensive place on Earth, half-year-shrouded. People still live here. They set up the research stations in which they live and work. In these extreme climatic conditions, the station originates and disappears due to natural behaving. Stations provide researchers with safety and space for research, including comfort. They are built in different ways and provide different comforts, according to technological and transport options.
Project - Organization of Dance Marathon
Fikejzová, Kristýna ; Mach, Jan (referee) ; Kysel, Jiří (advisor)
This bachelor thesis deals with organization of dance marathon. In a theoretical part some terms are characterized, such as a manager, project management and sport marketing. The readers are also given information about dance features and characteristics. I used the survey and SWOT analysis to analyze the present state. Furthermore I deal with preparation and organization of dance marathon including the proposals for its innovation.
Design optimisation and strenght checking of Water tiltable devices
Mach, Jan ; Holub, Michal (referee) ; Knoflíček, Radek (advisor)
This master’s thesis is about possibility of fruit and vegetable process from agricultural raw material to food. The first part of thesis include information about machinery, devices and process line and describe how this devices work. The second part solve water tiltable device, this part explain what water tiltable device do, how work and describe structure of each subassembly. Next step solve the device by kinematics aspect and aspect of load analysis. Calculation is included in annex one. Results of annex one are used for FEM (finite element method) simulation of frame. Output of FEM simulation can be used for finding safety factor of displacement and strain, output data are used for optimization of device.
Possibility of hazardous environment monitoring
Mach, Jan ; Musil, Martin (referee) ; Blecha, Petr (advisor)
This bachelor’s thesis is about mobile robotics and usage it in electricity industry. First part solve ability of taking the fences and provide basic facts about mobile robotics, kind of chassis and purpose of usage to reader. Second part includes concepts of truck and position device with monitoring system. This concepts solve submission with reference to utility of monitoring device, mobile robot and price. Output of this work is constructive solving of mobile monitoring robot.
Anti-Plagiarism Services For Our Repositories
Mach, Jan
The presentation is focused on a comparative analysis of systems for detecting duplicates (called anti-plagiarism systems) suitable for repositories of ETDs in the Czech Republic. The paper describes the testing process and results. These results can help to decide, which system will be suitable as a anti-plagiarism tool for the control of theses and other types of gray literature.
Fulltext: idr-692_3 - Download fulltextPDF
Slides: idr-692_1 - Download fulltextPDF; idr-692_2 - Download fulltextPDF
Video: idr-692_4 - Download fulltextMP4
ERP as a Service
Mach, Jan ; Voříšek, Jiří (advisor) ; Kopecký, Roman (referee)
This work is focused on the problematics of ERP as a Service and its main goal is to identify opportunities for new Czech providers of ERP as a Service. In theoretical part of this work at first is described that, what is provided by ERP as a Service. Further off is this part focused on that, how and under which terms can be and should be ERP as a Service provided. In last chapter of this part are presented world IT trends (for example Lean IT) and its relation to ERP as a Service. In second part of this work was documented the analysis of selected providers of ERP as a Service. That analysis helped to identify opportunities for new providers of ERP as a Service and also determine advices for new or selected providers of ERP as a Service. Creation of the method of the analysis was based on ideal of the provider of ERP as a Service and its product, which is described in first part of this work. In the analysis was also found some characteristics of Czech market of ERP as a Service and its providers. Benefits of this work are not only pointed at providers of ERP as a Service, but also at its potential customers. They can for example find out in this work on what they should focus on or what they should beware of when choosing ERP as a Service.

National Repository of Grey Literature : 39 records found   beginprevious21 - 30next  jump to record:
See also: similar author names
20 MACH, Jan
15 MACH, Jiří
8 Mach, Jakub
1 Mach, Jaroslav
1 Mach, Jindřich
15 Mach, Jiří
2 Mach, Jonáš
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