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No exact match found for Kuchynka,, Michaela, using Kuchynka Michaela instead...

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Optimizing experimental parameters for LIBS analysis of hard tissues Fazlić, Aida ; Kuchynka,, Michaela (referee) ; Pořízka, Pavel (advisor) Tato diplomová práce se zaměřuje na detekci a analýzu těžkých kovů, zejména olova (Pb), v tvrdých tkáních pomocí hydroxyapatitových standardů a spektroskopie laserem buzeného plazmatu (LIBS). Studie využívala různé vlnové délky laseru 1064 nm, 532 nm a 266 nm, stejně jako různé konfigurace laseru, včetně jednopulzní (SP, z angl. single-pulse) LIBS a dvojpulzní (DP, z angl. double-pulse) LIBS v ortogonálním a kolineárním uspořádání. Byla provedena optimalizace parametrů laseru, jako jsou vlnová délka, defokus, doba zpoždění, mezipulzní doba zpoždění a energie. Poměr signál-ke-šumu (SBR), limit detekce a rozlišení odpovídající průměru ablačního kráteru sloužily jako základní parametry pro určení optimální kombinace parametrů. Výsledky této studie poskytují důležité poznatky o optimálních parametrech LIBS pro detekci a analýzu těžkých kovů v tvrdých tkáních, což může mít potenciálně významné dopady pro lékařský výzkum. Detailed record

Optimization of laser ablation of soft tissues Bischofová, Hana ; Kuchyňka,, Michaela (referee) ; Pořízka, Pavel (advisor) Laser-induced breakdown spectroscopy (LIBS) is an analytical method which is used in many fields and also for elemental analysis of soft tissues. It is necessary to optimize the soft tissue laser ablation to achieve the highest possible intensity of the wavelength spectrum. Mouse kidneys were ablated in the experimental part of this master thesis. The samples of the kidneys were prepared in two different ways, by embedding in paraffin and by preparing cryo-sections. The femto- and the nano- second lasers with different wavelengths, energies and pulse counts were used for ablation. Detailed record

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