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Antiaggregant Therapy and Possibility of its Monitoring in Ischaemic Heart Disease
Kašparová, Markéta ; Hrdina, Radomír (advisor) ; Gregor, Jaroslav (referee)
The effect of antiaggregation therapy is an important factor that can influence the risk of thromboembolic events. The methods of monitoring antiaggregation therapy we compared in our study. The aggregation with cationic propylgallate (CPG) as the activating substance, analyzer PFA-100, which investigates the function of primary haemostasis and measuring of TXB2 in the urine were used to monitor the effect of the therapy. The sufficient concentration of CPG (30 mol/l) in the aggregation study were confirmed. The influence of hospitalization and associated stress on the parameters of aggregation was not significant. However the decrease of parameter of aggregation (slope, %/min) after administration of a low dose of acetylsalicylic acid (ASA) was significant. The influence of stress linked to hospitalization on the detected closure time (CT), was not observed using PFA 100. Nevertheless antiaggregation therapy significantly prolonged CT measured on the collagen/epinephrine coated membrane. The concentration of the thromboxane B2 in the urine of patients treated with antiaggregation therapy was also significantly lower in the contrary to healthy donators. The methods reacted after administration of low doses ASA by modifying of measured parameters. Fifty one patients treated with long term...
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Role of music group Extempore in the czech underground
Kašparová, Markéta ; Míšková, Alena (advisor) ; Koura, Petr (referee)
This thesis deals with the music group Extempore since its foundation by Jaroslav Jeronym Neduha in 1973 until its annulment by Mikolas Chadima in 1981. The thesis shows the important moments of the group and its members. Jaroslav Jeronym Neduha was Extempore's frontman by the year 1979 then he left the group and its management handed to Mikolas Chadima. Both gave to Extempore its characteristic style in the musical aspect, lyrics and performance. Extempore gained lots of fans, so the State Security focused on them as a obnoxius music group. The thesis has the aim to reveal Extempore's role in Czech musical underground. Firstly I defined alternative culture in relation to underground and official culture with focus to the music. Also I described Prague's unofficial big beat scene between 1973 - 1981. Primarily the thesis is focused on alternative music scene and musical underground. The review also contains other noncommercial movements during that time - folk association Safran and younger musical movement New Wave that inspirated Chadima's Extempore. Since the 1979 Extempore has been more and more pressed to the illegality until they got ban to perform their music in any Prague's club. Anyways they pushed for public performances and they kept up in free creation. An important outcome is fact that...
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Role of music group Extempore in the czech underground
Kašparová, Markéta ; Míšková, Alena (advisor) ; Koura, Petr (referee)
This thesis deals with the music group Extempore since its foundation by Jaroslav Jeronym Neduha in 1973 until its annulment by Mikolas Chadima in 1981. The thesis shows the important moments of the group and its members. Jaroslav Jeronym Neduha was Extempore's frontman by the year 1979 then he left the group and its management handed to Mikolas Chadima. Both gave to Extempore its characteristic style in the musical aspect, lyrics and performance. Extempore gained lots of fans, so the State Security focused on them as a obnoxius music group. The thesis has the aim to reveal Extempore's role in Czech musical underground. Firstly I defined alternative culture in relation to underground and official culture with focus to the music. Also I described Prague's unofficial big beat scene between 1973 - 1981. Primarily the thesis is focused on alternative music scene and musical underground. The review also contains other noncommercial movements during that time - folk association Safran and younger musical movement New Wave that inspirated Chadima's Extempore. Since the 1979 Extempore has been more and more pressed to the illegality until they got ban to perform their music in any Prague's club. Anyways they pushed for public performances and they kept up in free creation. An important outcome is fact that...
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Antiaggregant Therapy and Possibility of its Monitoring in Ischaemic Heart Disease
Kašparová, Markéta ; Hrdina, Radomír (advisor) ; Gregor, Jaroslav (referee)
The effect of antiaggregation therapy is an important factor that can influence the risk of thromboembolic events. The methods of monitoring antiaggregation therapy we compared in our study. The aggregation with cationic propylgallate (CPG) as the activating substance, analyzer PFA-100, which investigates the function of primary haemostasis and measuring of TXB2 in the urine were used to monitor the effect of the therapy. The sufficient concentration of CPG (30 mol/l) in the aggregation study were confirmed. The influence of hospitalization and associated stress on the parameters of aggregation was not significant. However the decrease of parameter of aggregation (slope, %/min) after administration of a low dose of acetylsalicylic acid (ASA) was significant. The influence of stress linked to hospitalization on the detected closure time (CT), was not observed using PFA 100. Nevertheless antiaggregation therapy significantly prolonged CT measured on the collagen/epinephrine coated membrane. The concentration of the thromboxane B2 in the urine of patients treated with antiaggregation therapy was also significantly lower in the contrary to healthy donators. The methods reacted after administration of low doses ASA by modifying of measured parameters. Fifty one patients treated with long term...
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Vliv alelopatických látek obsažených v biomase Ambrosia artemisiifolia L. na vybrané rostliny a odhad aktuálních rizik pro zemědělskou produkci
Kašparová, Markéta
The effect of the allelopathic substances contained in Ambrosia artemisiifolia L. was monitored on selected plant species. As an accompanying plants Common wheat (Triticum aestivum L.) - spring form, Common Bird's-foot Trefoil (Lotus corniculatus L.), Red Clover (Trifolium pratense L.), Red Fescue (Festuca rubra L.), Timothy grass (Phleum pratense L.), Tall oat-grass (Arrhenatherum elatius L.) and Ribwort (Plantago lanceolata L.) were selected. In cultivation experiments were used extracts from the aerial parts of common ragweed, root extracts and common ragweed plant sown to the tested plants. From the values obtained in cultivation experiments the influence of common ragweed on selected plant species and its impact on agricultural production was evaluated.
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