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Functional Movement Disorders in Neurology and the Role of Physiotherapy in their Treatment
Němcová, Daniela ; Jeníček, Jakub (advisor) ; Kejhová, Eva (referee)
OF BACHELOR THESIS Author: Daniela Němcová Supervisor: Mgr. Jakub Jeníček, Ph.D. Consultant: Mgr. Martin Jirásek Title: Functional movement disorders in neurology and the role of physiotherapy in their treatment Abstract: The bachelor thesis focuses on the issue of functional movement disorders in neurology. This work is of a theoretical-practical type with emphasis on the theoretical part. Although functional movement disorders present a common diagnosis, this topic is inadequately explored, controversial and of low popularity. Therefore, it remains unknown for many health professionals. The theoretical part of the thesis contains chapters describing the definition and terminology pitfalls, characteristic clinical manifestations and anamnestic data, historical context of this issue and an overview of the current pathophysiological findings. Also, the characteristics of the most common forms of functional movement disorders are covered, including the clinical differences from their organic counterparts and the specific features and clinical testing used when establishing the diagnosis. The theoretical part also includes chapters mapping the process and particular steps of the treatment and the possible treatment methods for the functional movement disorder patients. The theoretical part is...
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Use of Mulligan Mobilization Techniques in Patients with Distortion of Ankle Joint
Navrátilová, Monika ; Plevová, Kristýna (advisor) ; Jeníček, Jakub (referee)
Title: Use of Mulligan Mobilization Techniques in Patients with Distortion of Ankle Joint Abstract: This bachelor thesis deals with distortion of ankle joint and Mulligan Concept application issues. The main purpose of the thesis is to use the Mobilizations with Movement techniques (hereinafter referred to as MWM) in patients who suffered ankle joint sprain. With the thesis being divided into theoretical and practical parts, the former one presents the issue of ankle joint using anatomic point of view and kinesiology viewpoint. The following chapter deals with ankle joint distortion with regards to its most frequent cause, a risk of development of CAI (chronic ankle instability), appropriate treatment and physiotherapy. At the end of theoretical part is presented Brian Mulligan and his concept. The practical parts consists of casuistry on two themes. Both of them include initial examination, therapy goals definition, description of physiotherapy intervention and final examination. In order to be able to assess therapy results, the author chooses the Knee to Wall Test and Two-scale-stand Test methods as parts of both initial and final examination. In addition, the author compares initial and final values of ankle joint locomotion extent goniometric gauging, lower limbs girth anthropometric gauging, pain...
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Preparation of the high-affinity binding domain of protein B7-H6
Jeníček, Jakub ; Vaněk, Ondřej (advisor) ; Čermáková, Michaela (referee)
Natural killer cells are part of innate immunity and play a key role in defending the organism. Their role in the defense against tumors and anti-tumor therapy has been the subject of multiple research projects because tumors are among the most frequent causes of death worldwide. Tumor therapy is often complicated and invasive; therefore, finding new therapeutic approaches that target naturally occurring defense mechanisms is advantageous. One of the key mechanisms used by NK cells to recognize tumor cells and eliminate them is signaling via their receptor NKp30. The binding of an activation ligand to this receptor can induce the activation of a cytotoxic response, leading to the elimination of the tumor cell. One of the activating ligands that can bind to NKp30 is B7-H6, a cell surface protein found on certain types of tumors. However, the interaction between B7-H6 and NKp30 has not been wholly described yet. This thesis focuses on different methods, which can be used for obtaining the B7-H6 domain bearing a fluorescent label, that could be used to visualize NKp30 on the cell surface, thus allowing for further description of the interaction between these molecules. KEY WORDS NK cells, NKp30, B7-H6, sortase A, HEK293
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Physiotherapy in patients with medial epicondylitis of sports-related etiology. Subtitle: With a focus on baseball players
Imramovský, Jan ; Jeníček, Jakub (advisor) ; Kozel, Jakub (referee)
BACHELOR THESIS ABSTRACT Author: Jan Imramovský Supervisor: Mgr. Jakub Jeníček, Ph.D. Title: Physiotherapy in patients with medial epicondylitis of sports-related etiology. With a focus on baseball players Abstract: The bachelor thesis is of a theoretical-practical type. The thesis deals with problematics of medial epicondylitis in baseball players. Medial epicondylitis is a widely known condition. However, baseball players are atypical population with atypical needs in terms of specific approach in prevention, treatment and returning to sport. The theoretical part of the bachelor thesis provides in three parts a comprehensive insight into studied area. The first part describes relevant anatomy, histology nad kinesiology of the elbow. The second part contains an introduction into baseball as a game and in particular its most specific motion, the pitiching motion. Part three discusses the epidemiology, etiopatogenesis, clinical picture, diagnostics and both conservative and radical approach to treatment of medial epicondylitis. The practical part of the thesis has two objectives. The main goal was to develop an intervention manual for the physiotherapy treament of medial epicondylitis in baseball players. This manual offers a guidance for a complex physiotherapeutical treatment of this condition and a return...
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Dual-Task Program in Neurorehabilitation in Patients with Acquired Brain Injury
Burdová, Eliška ; Jeníček, Jakub (advisor) ; Krivošíková, Mária (referee)
This diploma thesis deals with the topic of the use of the dual task in neurorehabilitation in patients with aquired brain injury. Its main goal was to create a program using dual task procedures, which was subsequently applied in a cognitively focused daily rehabilitation stationary of the The Department of Rehabilitation Medicine of the General Hospital and the First Medical Faculty of Charles University. Another goal was to provide settings for using the conditions of the program, its evaluation and finding out whether it was applied to the patient to improve some of the ADL. The research part of the work is processed by the method of qualitative evaluation research through the elaboration of one case study and evaluation of the program by a decision evaluation model. Based on a comprehensive search, a therapeutic program was developed and evaluated. It includes three levels of primary motor tasks and secondary cognitive tasks divided according to specific cognitive functions. This is a pilot study to further investigate the effect of the use of the dual task in people with aquired brain injury. Key words: dual-task, cognitive-motor interference, neurorehabilitation, acquired brain injury
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The Use of Peroneal Nerve Functional Electrical Stimulation in Patients with Spastic Paresis
Vítek, Jakub ; Jeníček, Jakub (advisor) ; Šebek, Milan (referee)
OF BACHELOR THESIS Title: The Use of Peroneal Nerve Functional Electrical Stimulation in Patients with Spastic Paresis Subtitle: Clinical Assessment of Novel Device for Functional Electrical Stimulation Background: Peroneal Nerve Functional Electrical Stimulation is a method used to compensate foot drop syndrome, which can be often seen in patients with spastic paresis. Foot drop syndrome limits lower extremity function, impairs mobility and represents a considerable risk of falling. Due to the frequent occurrence of these difficulties and their severity new compensation and therapeutic devices are being developed. Objective: The main purpose of the thesis was to use novel device for functional electrical stimulation (FES) in patients with spastic paresis and describe its functionality, reliability, ergonomics and user-friendliness from the perspective of both therapist and patient. Methods: Two probands, diagnosed with spastic paresis, participated in a two-week trial of the prototype device which offers new options of multi-channel stimulation and setting of all stimulation parameters directly in the device using the touch screen. After the intervention a semi-structured interview and a survey, which were focused on the device abilities, were administered with probands. The interview and the...
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Effect of electrical stimulation on soft tissue healing
Fošumpaur, Karel ; Jeníček, Jakub (advisor) ; Angerová, Yvona (referee)
First and last name: Karel Fošumpaur Supervisor: Mgr. Jakub Jeníček, Ph.D. Opponent of the thesis: Name of the thesis: Effect of electrical stimulation on soft tissue healing Abstract of the thesis: This bachelor thesis summarizes the current state of knowledge regarding the effectiveness of electrical stimulation on soft tissue healing by providing an overview of the issue. The aim of the thesis is to describe the current level of research on the subject in terms of its completeness, current stage and limitations. Fifteen peer-reviewed, relevant articles were included and analyzed through a systematic search. Through analytical analysis and evaluation of the studies, it is determined whether and under what conditions electrical stimulation is effective for soft tissue healing. The articles presented include studies testing the effectiveness of electrical stimulation for healing structurally damaged muscle, tendon, skin and ligament. The work provides a largely positive conclusion regarding the healing effect of electrical stimulation. Key words: electrical stimulation, healing, soft tissue, muscle, tendon, skin, connective tissue, ligament, regeneration, reparation, electrotherapy
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Using the system of StereoBalance for training mechanisms of stabilization
Brázdilová, Kateřina ; Tichá, Marie (advisor) ; Jeníček, Jakub (referee)
Author's first name and surname: Kateřina Brázdilová Bachelor thesis supervizor: MUDr. Marie Tichá Oponent: Title of bachelor thesis: Using the system of StereoBalance for training mechanisms of stabilization. Abstract: The bachelor thesis is focused on disorders of postural stability of patients after brain damage. The brain damage is classified as very serious health condition, which can be caused by traumatic brain injuries, post-stroke or as a consequences of cancer, neurodegenerative diseases, etc. The brain damage may develop disorder of postural stability, which is manifested by feelings of insecurity of standing, walking, increased frequency of falls and dizziness. This work is not based on classical physiotherapy techniques. Aplication of this therapy uses stabilometric platforms and 3D scenes in virtual reality. The therapy consists of testing the stability of standing and therapy in program StereoBalance. Therapies were absolved by two patiens post-stroke. To be able to compare the results of patients with postural stability disorder, healthy population was also examined (10 probands). The aim of the study is to determine the effect of this therapy in program StereoBalance on postural stability disorders. Key words: Postural stability, stroke, stabilometry, virtual reality, stabilometric...
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Comparison of Orthotic Effect between an Ankle Foot Orthosis and a Functional Peroneal Electrostimulation on Gait in Patients after Stroke.
Lučanská, Veronika ; Jeníček, Jakub (advisor) ; Drábová, Zuzana (referee)
Name: Veronika Lučanská Supervisor: Mgr. Jakub Jeníček Opponent: Title of bachelor thesis: Comparison of Orthotic Effect between an Ankle Foot Orthosis and a Functional Peroneal Electrostimulation on Gait in Patients after Stroke. Abstract: This bachelor's thesis is focused on comparing orthotic effect between an ankle foot orthosis and a functional peroneal electrostimulation on gait in patients after stroke. The goal of this thesis is to evaluate and compare orthotic effect of AFO and FPES. Footscan® and video analysis were both used for examining gait. This thesis consists of both theoretical and practical sections. The theoretical part contains basic knowledge on stroke and hemiparetic gait, focusing on foot-drop. It also contains a review of several studies describing the effect ofAFO and FPES. In practical section of this thesis, two different patients will be used as case studies. These patients were measured without any aid, with AFO and then again with FPES. The variables evaluated are velocity of gait, length of stance phase, movement of center of plantar pressure and gait stereotype. Data from dynamic plantography is then evaluated and compared via tables, graphs and via photos. Key words: stroke, foot-drop, functional electrostimulation, ankle foot orthosis, footscan
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Objective assessment of stability disorders in patients after brain damage
Studená, Vendula ; Tichá, Marie (advisor) ; Jeníček, Jakub (referee)
The bachelor thesis deals with virtual reality balance therapy. The therapy focuses on chronic patient after brain damage. The first - theoretical part of the thesis contains especially definitions of biofeedback and virtual relality. It analyses possibilities of balance testing in detail. The second - practical part of the thesis includes description of a virtual environment developed at the Joint Department of Biomedical Engineering of Czech Technical University and Charles University in Prague. The input and output examinations of two patients are compared and results of the therapy are evaluated. The examinations consist of subjective MiniBESTest and objective posturographic Complete Static Sensory Organization Test (CSSOT) and Faller Assessment. An objectification of the instantaneous effect of the therapy is evaluated by virtual reality games. The discusion compares patient's and control group's examination findings. The results of the MiniBESTest, CSSOT and velocity of movement in virtual enviroment show improvement in postural stability. Key words: virtual reality, postural stability, balance testing, posturography, brain damage, balance board
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