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Evaluation of the impact of technical and technological adjustments to the water treatment plant on the quality of treated water
Jedličková, Ivana ; Látal,, Milan (referee) ; Kučera, Tomáš (advisor)
The subject of this bachelor thesis is the evaluation of sequential technical and technological changes of water collection and modification at a specific water treatment facility – the water treatment facility in Ivančice. The first part of the thesis explains the basic terminology such as technological processes of the water treatment plant, types of water treatment facilities, the range of different types of water based on its quality and technologies that can be found at the water treatment plant in Ivančice. The next two chapters describe the water treatment process before and after intensification. The primary focus is on raw water collection, the quality of both raw and treated water, and the water treatment technology. The last part of the paper offers multiple comparisons of the original and renovated facility and recommendations for improving the operations of the renovated water treatment facility. The final evaluation was carried out based on the information collected mainly by visiting the facility in person, and other sources.
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Pilot study on the risk assessment of selected water supply
Jedličková, Ivana ; Svoboda,, Miroslav (referee) ; Kučera, Tomáš (advisor)
This diploma thesis focuses on risk evaluation of water line for public use. The risk analysis is done in compliance with the methodology created by VODÁRENSKÁ AKCIOVÁ SPOLEČNOST, a. s. and by the method WaterRisk, created by Institute of Municipal Water management, Brno University of Technology, Faculty of Civil Engineering. The thesis clarifies the key points of the topic in question. Its readiness for passing in the Czech Republic and its core in relation to legislature. Then the thesis also includes a description of a specific water line. In the following two chapters the risks are studied according to the methodologies chosen.
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Genetic and molecular basis of neurodegenerative and neuropsychiatric diseases
Jedličková, Ivana ; Kmoch, Stanislav (advisor) ; Fajkusová, Lenka (referee) ; Laššuthová, Petra (referee)
Next-generation (NGS) and third-generation (TGS) sequencing methods have played a key role in strategies of disease genes identification. Especially the exome sequencing increased the efficiency of causal variants identification up to tens of percent in study cohorts. Rare neurodegenerative diseases are clinically and genetically heterogeneous and show a broad differential diagnostics. NGS and TGS technologies have been crucial in our understanding of the pathomechanism of rare neurodegenerative diseases. NGS and TGS, used by research laboratories, have been essential for many patients to determine a correct diagnosis, provide genetic counselling and reach an adequate treatment. This thesis focuses on molecular mechanisms of selected rare neurodegenerative diseases, namely adult neuronal ceroid lipofuscinosis (ANCL), spinal muscular atrophy (SMA) and neuronal intranuclear inclusion disease (NIID). Modern DNA sequencing methods led to identification of causal lesions in ANCL suspect patients. We provide a concept of genetic testing for SMN1 negative SMA patients and present a method for validation of tandem repeat expansion in NIID. Key words: adult neuronal ceroid lipofuscinosis, spinal muscular atrophy, neuronal intranuclear inclusion disease, next-generation sequencing methods, DNAJC5
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Pilot study on the risk assessment of selected water supply
Jedličková, Ivana ; Svoboda,, Miroslav (referee) ; Kučera, Tomáš (advisor)
This diploma thesis focuses on risk evaluation of water line for public use. The risk analysis is done in compliance with the methodology created by VODÁRENSKÁ AKCIOVÁ SPOLEČNOST, a. s. and by the method WaterRisk, created by Institute of Municipal Water management, Brno University of Technology, Faculty of Civil Engineering. The thesis clarifies the key points of the topic in question. Its readiness for passing in the Czech Republic and its core in relation to legislature. Then the thesis also includes a description of a specific water line. In the following two chapters the risks are studied according to the methodologies chosen.
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Evaluation of the impact of technical and technological adjustments to the water treatment plant on the quality of treated water
Jedličková, Ivana ; Látal,, Milan (referee) ; Kučera, Tomáš (advisor)
The subject of this bachelor thesis is the evaluation of sequential technical and technological changes of water collection and modification at a specific water treatment facility – the water treatment facility in Ivančice. The first part of the thesis explains the basic terminology such as technological processes of the water treatment plant, types of water treatment facilities, the range of different types of water based on its quality and technologies that can be found at the water treatment plant in Ivančice. The next two chapters describe the water treatment process before and after intensification. The primary focus is on raw water collection, the quality of both raw and treated water, and the water treatment technology. The last part of the paper offers multiple comparisons of the original and renovated facility and recommendations for improving the operations of the renovated water treatment facility. The final evaluation was carried out based on the information collected mainly by visiting the facility in person, and other sources.
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