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Deposition of particles in a model of human lungs
Jakuš, Matúš ; Tuhovčák, Ján (referee) ; Bělka, Miloslav (advisor)
The main purpose of thesis was to do a research of methods suitable for measuring the deposition of particles in human airways. Thesis also contains experiment with porous particles and evaluation of created samples using phase-contrast microscopy. Porous particles seem to be appropriate option for delivering drugs or therapeutic aerosol into the human airways and that made them very interesting in past few years. Theoretical basics of physiology of human airways, aerosols, physical principles of particle deposition and realistic model used during experiment are also explained in this study.
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Deposition of particles in a model of human lungs
Jakuš, Matúš ; Tuhovčák, Ján (referee) ; Bělka, Miloslav (advisor)
The main purpose of thesis was to do a research of methods suitable for measuring the deposition of particles in human airways. Thesis also contains experiment with porous particles and evaluation of created samples using phase-contrast microscopy. Porous particles seem to be appropriate option for delivering drugs or therapeutic aerosol into the human airways and that made them very interesting in past few years. Theoretical basics of physiology of human airways, aerosols, physical principles of particle deposition and realistic model used during experiment are also explained in this study.
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