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Operating Characteristics of LED Sources
Brdečko, Aleš ; Diviš, Daniel (referee) ; Baxant, Petr (advisor)
This semester thesis is dealing with issues of LED (light emiting diod).In the text we can find general summary knowledges about LED, relating their history, construction, principle of working and also treatise about of semiconductor compounds. In thesis are given examples of use indicating their advantages and disadvantages and indicating their parameters. The practical content of this thesis is evaluation of measurement performed on some samples of LED especially graphics addiction of crosses and V-A characteristics measured in addiction on current.
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The role of miR-150 in the physiopathology of oligoarticular juvenile idiopathic arthritis
Diviš, Daniel ; Pávek, Petr (advisor) ; Soukup, Tomáš (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Daniel Diviš Supervisors: Prof. Dr. Florence Apparailly, Directrice de Recherche Prof. PharmDr. Petr Pávek, Ph.D. (formal tutor) Title of diploma thesis: The role of miR-150 in the physiopathology of oligoarticular juvenile idiopathic arthritis Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatoid disease affecting children, and its pathological mechanisms are still poorly understood. Innate and adaptive immunity including myeloid cells play a major role in these processes. Epigenetic deregulations along with non-coding microRNAs have been reported in many inflammatory diseases. Moreover, preliminary results obtained by the research group of Prof. Florence Apparailly showed accumulation of intermediate monocytes along with the high expression of miR-150 in the synovial fluid of children affected by oligoarticular JIA. Based on these findings a hypothesis has been postulated suggesting that miR-150 could have a role in the pathogenesis of this disease and in the regulation of monocyte differentiation and function. To study the impact of miR-150 on monocytes from the peripheral blood of healthy donors, transfection experiments were performed to neutralize miR-150. The...
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The role of miR-150 in the physiopathology of oligoarticular juvenile idiopathic arthritis
Diviš, Daniel ; Pávek, Petr (advisor) ; Soukup, Tomáš (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Daniel Diviš Supervisors: Prof. Dr. Florence Apparailly, Directrice de Recherche Prof. PharmDr. Petr Pávek, Ph.D. (formal tutor) Title of diploma thesis: The role of miR-150 in the physiopathology of oligoarticular juvenile idiopathic arthritis Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatoid disease affecting children, and its pathological mechanisms are still poorly understood. Innate and adaptive immunity including myeloid cells play a major role in these processes. Epigenetic deregulations along with non-coding microRNAs have been reported in many inflammatory diseases. Moreover, preliminary results obtained by the research group of Prof. Florence Apparailly showed accumulation of intermediate monocytes along with the high expression of miR-150 in the synovial fluid of children affected by oligoarticular JIA. Based on these findings a hypothesis has been postulated suggesting that miR-150 could have a role in the pathogenesis of this disease and in the regulation of monocyte differentiation and function. To study the impact of miR-150 on monocytes from the peripheral blood of healthy donors, transfection experiments were performed to neutralize miR-150. The...
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Operating Characteristics of LED Sources
Brdečko, Aleš ; Diviš, Daniel (referee) ; Baxant, Petr (advisor)
This semester thesis is dealing with issues of LED (light emiting diod).In the text we can find general summary knowledges about LED, relating their history, construction, principle of working and also treatise about of semiconductor compounds. In thesis are given examples of use indicating their advantages and disadvantages and indicating their parameters. The practical content of this thesis is evaluation of measurement performed on some samples of LED especially graphics addiction of crosses and V-A characteristics measured in addiction on current.
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