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National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Utilization of CTA and CTP in Middle Cerebral Artery Stroke
 Cimflová, Petra ; Krajina, Antonín (advisor) ; Neuwirth, Jiří (referee) ; Procházka, Václav (referee)
Introduction: Diagnostic imaging has a crucial role in the diagnosis and therapeutic management of acute ischemic stroke (AIS). The main aim of this thesis was to further evaluate the utilization of CTA and CT perfusion (CTP) in the diagnosis and treatment decision in patients with AIS caused by the occlusion of the middle cerebral artery. Methods: Study in Chapter 2 evaluated the automatically derived CT perfusion lesion volumes (PLV) and hypoperfusion intensity ratio (HIR) with collateral score using multiphase CTA (mCTA) (Kruskal-Wallis, Wilcoxon rank-sum test and Spearman's rho correlation coefficients were calculated). In study in Chapter 3, the assessment of ischemic changes by expert reading and available automated software for non-contrast CT and CTP was compared (the sensitivity, specificity, positive and negative predictive value were calculated). In Chapter 4, the performance of StrokeSENS software tool in detection of anterior large vessel occlusions (LVO) was tested (receiver operator characteristics analysis). Study in Chapter 5 investigated whether prediction of clinical outcome and final infarct volume can be improved by collateral status assessment on time-variant color-coded mCTA (multivariable logistic regression). The aims in Chapter 6 were to determine if mCTA-derived tissue...
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