|
|
The use of the Internet in the teaching of mathematics
Brázdová, Marie ; Vondrová, Naďa (advisor) ; Jančařík, Antonín (referee)
The thesis focuses on information and communication technologies in education. It mainly deals with the use of the Internet in the teaching of mathematics at lower and upper secondary schools. The aim of the thesis is to summarize some information concerning the present knowledge of information and communication technologies in education and their impact on the process of education, to present various ways of using the Internet by maths teachers and to conduct an enquiry into the present state of the use of the Internet by maths teachers at lower and upper secondary schools. The thesis provides information about interesting mathematical Internet resources and examples of their use in a teacher's preparation for lessons and in mathematics lessons, too. The resources mentioned in the work should contribute to the improvement in the efficiency of the teaching of mathematics. The thesis shows that the Internet is a beneficial source which could improve the quality of the teaching of mathematics and education in general.
|
|
|
THE WAYS OF ACTIVATING TP53
Polášková, Alena ; Helma, Robert ; Adámik, Matěj ; Hronešová, L. ; Holacka, K. ; Ballová, L. ; Brázdová, Marie
P53, AGENTS, CELLS,P53, AGENTS, CELLS,P53, AGENTS, CELLS,P53, AGENTS, CELLS
|
|
|
DNA POLYMERASE STOP ASSAY FOR DETECTION OF G-QUADRUPLEXES
Petr, Marek ; Bažantová, Pavla ; Adámik, Matěj ; Kejnovská, Iva ; Dvořáková, Zuzana ; Vorlíčková, Michaela ; Pečinka, Petr ; Brázdová, Marie
In this work we performed DNA polymerase stop assays while using template DNA derived from promoter regions of VEGF and c-Myc proto-oncogenes under variety of experimental conditions. Partial stopping of DNA synthesis along the template strand was observed in the presence of K+ ions due to formation of stable G-quadruplex structures. In contrast, Na+ ions alone were unable to stabilize G-quadruplexes to stop the reaction at their site. These data suggest that K+ and Na+ ions, which are both known to stabilize G-quadruplexes, do this in different manner or extent.
|
|
|
ANALYSIS OF SEQUENCE SPECIFIC INTERACTIONS BETWEEN DNA AND P53 FAMILY PROTEINS BY ELISA, SLOT-BLOT AND EMSA
Adámik, Matěj ; Holanová, L. ; Navrátilová, Lucie ; Nygrinova, J. ; Pokorova, J. ; Petr, Marek ; Tichý, Vlastimil ; Brázdová, Marie
DNA-protein interactions of core domains of p53, p63 and p73, members of tumor suppressor p53 family, were investigated by multiple methods with regard to verifying the sequence specificity with which short target oligonucleotides/long DNA fragments can be recognized. The sequence specificity of core domains and wtp53 full protein binding to specific sequence in both types of DNA substrates was confirmed in solution, on surface and in gels by ELISA, slot-blot and EMSA.
|
|
| |
|
| |
|
|
Voltammetric Techniques for Analysis in a Single Drop of a Solution
Gajdar, J. ; Goněc, T. ; Jampílek, J. ; Brázdová, Marie ; Bábková, Zuzana ; Fojta, Miroslav ; Barek, J. ; Fischer, J.
This contribution describes miniaturization of voltammetric methods and some of the main problems caused by reducing the sample volume to 20 mu L. This study was carried out in dimethyl sulfoxide solutions and buffered aqueous solutions with 10% DMSO at a glassy carbon electrode. A novel antibiotic agent, 1-hydroxy-N-(4-nitrophenyl) naphthalene-2-carboxamide, was used as a model substance. This analyte was determined by cathodic and anodic voltammetry. Elimination of the negative influence of dissolved oxygen was performed in various manners. Two most effective methods were square wave voltammetry that can be used in the presence of dissolved oxygen and removal of oxygen in a microcell with nitrogen atmosphere inside.
|
|
| |
|
|
The use of the Internet in the teaching of mathematics
Brázdová, Marie ; Vondrová, Naďa (advisor) ; Jančařík, Antonín (referee)
The thesis focuses on information and communication technologies in education. It mainly deals with the use of the Internet in the teaching of mathematics at lower and upper secondary schools. The aim of the thesis is to summarize some information concerning the present knowledge of information and communication technologies in education and their impact on the process of education, to present various ways of using the Internet by maths teachers and to conduct an enquiry into the present state of the use of the Internet by maths teachers at lower and upper secondary schools. The thesis provides information about interesting mathematical Internet resources and examples of their use in a teacher's preparation for lessons and in mathematics lessons, too. The resources mentioned in the work should contribute to the improvement in the efficiency of the teaching of mathematics. The thesis shows that the Internet is a beneficial source which could improve the quality of the teaching of mathematics and education in general.
|
|
| |
guest ::
RSS feed.